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Details on Person UBE2N:UBE2V1 [cytosol]

Class:IdComplex:202463
_displayNameUBE2N:UBE2V1 [cytosol]
_timestamp2016-11-08 12:52:45
authored[InstanceEdit:202426] Garapati, P V, 2007-10-29 14:39:45
compartment[Compartment:70101] cytosol
created[InstanceEdit:202481] Garapati, P V, 2007-10-30 15:48:40
hasComponent
modified[InstanceEdit:446872] Jupe, S, 2009-11-18
[InstanceEdit:2980516] Jassal, B, 2013-01-11
[InstanceEdit:2997528] Jassal, B, 2013-01-23
[InstanceEdit:3209842] Jassal, B, 2013-03-04
[InstanceEdit:8948020] Jupe, Steve, 2016-11-08
nameUBE2N:UBE2V1
Ubc13:UBE2V1
TRAF6-regulated IKK activator 1
TRIKA1
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:364833] R-HSA-202463.2
(hasComponent)[Complex:450144] hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] [Homo sapiens]
[Complex:689001] TRAF2/5 E3-E2 ligase complex [cytosol] [Homo sapiens]
[Complex:1248657] TRAF6 E3/E2 ubiquitin ligase complex [cytosol] [Homo sapiens]
[Complex:8948058] K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] [Homo sapiens]
[Complex:8980241] IL17A dimer,IL17F dimer,IL17A:IL17F:IL17RA:IL17RC:TRAF3IP2:K63polyUb-TRAF6:UBE2N:UBE2V1 [plasma membrane] [Homo sapiens]
[Complex:9012090] p-IRAK1:TRAF6:UBE2N:UBE2V1 [plasma membrane] [Homo sapiens]
[Complex:9640491] Ub:UBE2N:UBE2V1 [cytosol] [Homo sapiens]
[Complex:9641124] UBE2N:UBE2V1:PRKN [cytosol] [Homo sapiens]
(hasMember)[DefinedSet:9834952] UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] [Homo sapiens]
(input)[Reaction:202453] Auto-ubiquitination of TRAF6 [Homo sapiens]
[BlackBoxEvent:202534] Ubiquitination of NEMO by TRAF6 [Homo sapiens]
[Reaction:937050] Pellino ubiquitinates hp-IRAK1 [Homo sapiens]
[BlackBoxEvent:975118] TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex [Homo sapiens]
[Reaction:975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
[Homo sapiens]

[BlackBoxEvent:2730904] Auto-ubiquitination of TRAF6 [Homo sapiens]
[BlackBoxEvent:5607756] TRAF6 oligomer autoubiquitinates [Homo sapiens]
[BlackBoxEvent:5607757] K63polyUb-TRAF6 ubiquitinates TAK1 [Homo sapiens]
[Reaction:8980295] Ubiquitylation of TRAF6 by TRAF3IP2 after IL17:IL17R interaction [Homo sapiens]
[Reaction:8980351] Ubiquitination of NEMO by polyUb-TRAF6:TAK1:TAB2:TAB3 complex [Homo sapiens]
List all 13 refering instances
(output)[Reaction:202453] Auto-ubiquitination of TRAF6 [Homo sapiens]
[BlackBoxEvent:202534] Ubiquitination of NEMO by TRAF6 [Homo sapiens]
[Reaction:937050] Pellino ubiquitinates hp-IRAK1 [Homo sapiens]
[BlackBoxEvent:975118] TRAF6 ubiquitinqtes IRF7 within the activated TLR7/8 or 9 complex [Homo sapiens]
[Reaction:975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
[Homo sapiens]

[BlackBoxEvent:2730904] Auto-ubiquitination of TRAF6 [Homo sapiens]
[BlackBoxEvent:5607756] TRAF6 oligomer autoubiquitinates [Homo sapiens]
[BlackBoxEvent:5607757] K63polyUb-TRAF6 ubiquitinates TAK1 [Homo sapiens]
[BlackBoxEvent:8948018] UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [Homo sapiens]
[BlackBoxEvent:8948066] K63polyUb-IRAK1 dissociates [Homo sapiens]
List all 12 refering instances
(requiredInputComponent)[BlackBoxEvent:450259] Auto ubiqitination of TRAF6 bound to viral dsRNS:TLR3:TICAM1 complex [Homo sapiens]
[Polymerisation:450358] Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation [Homo sapiens]
[BlackBoxEvent:936942] Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 [Homo sapiens]
[Polymerisation:936986] Activated TRAF6 synthesizes unanchored polyubiquitin chains [Homo sapiens]
[BlackBoxEvent:975147] Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane [Homo sapiens]
[Polymerisation:9628444] Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR3 stimulation [Homo sapiens]
[Polymerisation:9645394] Activated TRAF6 synthesizes unanchored polyubiquitin chains upon ALPK1:ADP-heptose stimulation [Homo sapiens]
[BlackBoxEvent:9645414] Auto ubiquitination of TRAF6 bound to ALPK1:ADP-heptose:TIFA oligomer [Homo sapiens]
[BlackBoxEvent:9834070] PRKN ubiquitinates MOM substrates [Homo sapiens]
(updatedInstance)[_UpdateTracker:9868449] Update Tracker - [Complex:202463] UBE2N:UBE2V1 [cytosol] - v31:[addName]
[_UpdateTracker:9879184] Update Tracker - [Complex:202463] UBE2N:UBE2V1 [cytosol] - v44:[add_removeHasComponent]
[_UpdateTracker:9884651] Update Tracker - [Complex:202463] UBE2N:UBE2V1 [cytosol] - v45:[add_removeHasComponent, modifyName]
[_UpdateTracker:9895625] Update Tracker - [Complex:202463] UBE2N:UBE2V1 [cytosol] - v59:[addName]
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No pathways have been reviewed or authored by UBE2N:UBE2V1 [cytosol] (202463)