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Details on Person PLC-gamma1 hydrolyses PIP2

Class:IdReaction:202407
_displayNamePLC-gamma1 hydrolyses PIP2
_doReleaseTRUE
_timestamp2020-02-25 18:41:20
authored[InstanceEdit:211006] Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
catalystActivity[CatalystActivity:202664] phosphatidylinositol-4,5-bisphosphate phospholipase C activity of p-PLCG [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:202250] Garapati, P V, 2007-10-29 14:08:25
edited[InstanceEdit:9675774] Murillo, Julieth, 2020-02-05
input[SimpleEntity:29356] H2O [cytosol]
[SimpleEntity:179856] PI(4,5)P2 [plasma membrane]
literatureReference[LiteratureReference:202392] The mechanism of phospholipase C-gamma1 regulation
modified[InstanceEdit:202491] Garapati, P V, 2007-10-30 16:01:01
[InstanceEdit:202573] Garapati, P V, 2007-11-05 11:22:29
[InstanceEdit:202663] Garapati, P V, 2007-11-08 10:35:56
[InstanceEdit:203257] Garapati, P V, 2007-11-12 15:37:54
[InstanceEdit:203526] Garapati, P V, 2007-11-14 09:28:17
[InstanceEdit:203529] Garapati, P V, 2007-11-14 10:24:07
[InstanceEdit:203950] Gopinathrao, G, 2007-11-20 16:27:22
[InstanceEdit:204115] de Bono, B, 2007-11-25 09:35:47
[InstanceEdit:212474] Garapati, P V, 2008-02-12 09:52:01
[InstanceEdit:213345] Gopinathrao, G, 2008-02-25 21:36:16
[InstanceEdit:213439] Garapati, P V, 2008-02-26 11:34:22
[InstanceEdit:214480] Garapati, P V, 2008-02-26 12:04:24
[InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06
[InstanceEdit:660810] D'Eustachio, P, 2010-05-01
[InstanceEdit:683441] Garapati, P V, 2010-05-06
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8984457] Duenas, Corina, 2017-04-06
[InstanceEdit:9673430] Murillo, Julieth, 2020-01-07
[InstanceEdit:9675994] Murillo, Julieth, 2020-02-06
[InstanceEdit:9677028] Murillo, Julieth, 2020-02-25
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePLC-gamma1 hydrolyses PIP2
output[SimpleEntity:112275] DAGs [plasma membrane]
[SimpleEntity:114520] I(1,4,5)P3 [cytosol]
precedingEvent
releaseDate2008-03-12
reviewed[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361344] R-HSA-202407.4
summation[Summation:203260] On recruitment to plasma membrane PLC-gamma1 then hydrolyses...
(hasEvent)[Pathway:202433] Generation of second messenger molecules [Homo sapiens]
[Pathway:9664323] FCGR3A-mediated IL10 synthesis [Homo sapiens]
(precedingEvent)[Reaction:169680] IP3 binds to the IP3 receptor, opening the endoplasmic reticulum Ca2+ channel [Homo sapiens]
[Reaction:202203] Recruitment of PI3K to plasma membrane [Homo sapiens]
(updatedInstance)[_UpdateTracker:9781182] Update Tracker - [Reaction:202407] PLC-gamma1 hydrolyses PIP2 - v61:[addLiteratureReference]
[_UpdateTracker:9790672] Update Tracker - [Reaction:202407] PLC-gamma1 hydrolyses PIP2 - v33:[add_removeOutput]
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No pathways have been reviewed or authored by PLC-gamma1 hydrolyses PIP2 (202407)
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