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Details on Person PI(3,4)P2 [plasma membrane]
| Class:Id | SimpleEntity:202247 |
| _displayName | PI(3,4)P2 [plasma membrane] |
| _timestamp | 2008-06-20 12:51:10 |
| authored | [InstanceEdit:201662] Garapati, P V, 2007-09-05 10:24:22 |
| compartment | [Compartment:876] plasma membrane |
| created | [InstanceEdit:202250] Garapati, P V, 2007-10-29 14:08:25 |
| modified | [InstanceEdit:9616752] Shorser, Solomon, 2018-08-13 [InstanceEdit:9619952] Wu, G, 2018-09-19 |
| name | PI(3,4)P2 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphates 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate |
| referenceEntity | [ReferenceMolecule:202393] 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate [ChEBI:16152] |
| stableIdentifier | [StableIdentifier:367448] R-ALL-202247.3 |
| (hasComponent) | [Complex:1861625] Actin filament bound Myosin-X [plasma membrane] [Homo sapiens] [Complex:8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane] [Homo sapiens] [Complex:8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane] [Homo sapiens] |
| (hasMember) | [DefinedSet:202277] PIP3, PI(3,4)P2 [plasma membrane] |
| (input) | [Reaction:1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane [Homo sapiens] [BlackBoxEvent:1675834] PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane [Homo sapiens] [Reaction:1676139] PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane [Mus musculus] [Reaction:1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane [Homo sapiens] [Reaction:1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane [Homo sapiens] [Reaction:1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner [Homo sapiens] [Reaction:8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2 [Homo sapiens] |
| (output) | [Reaction:202237] Hydrolysis of PIP3 to PI(3,4)P2 [Homo sapiens] [Reaction:1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane [Homo sapiens] [Reaction:1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane [Homo sapiens] [Reaction:1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane [Homo sapiens] [Reaction:8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 [Homo sapiens] |
| (regulator) | [PositiveRegulation:8868077] Positive regulation by 'PI(3,4)P2 [plasma membrane]' |
| (updatedInstance) | [_UpdateTracker:9890500] Update Tracker - [SimpleEntity:202247] PI(3,4)P2 [plasma membrane] - v52:[addName] |
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No pathways have been reviewed or authored by PI(3,4)P2 [plasma membrane] (202247)