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Details on Person PI(3,4)P2 [plasma membrane]

Class:IdSimpleEntity:202247
_displayNamePI(3,4)P2 [plasma membrane]
_timestamp2008-06-20 12:51:10
authored[InstanceEdit:201662] Garapati, P V, 2007-09-05 10:24:22
compartment[Compartment:876] plasma membrane
created[InstanceEdit:202250] Garapati, P V, 2007-10-29 14:08:25
modified[InstanceEdit:9616752] Shorser, Solomon, 2018-08-13
[InstanceEdit:9619952] Wu, G, 2018-09-19
namePI(3,4)P2
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphates
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate
referenceEntity[ReferenceMolecule:202393] 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate [ChEBI:16152]
stableIdentifier[StableIdentifier:367448] R-ALL-202247.3
(hasComponent)[Complex:1861625] Actin filament bound Myosin-X [plasma membrane] [Homo sapiens]
[Complex:8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane] [Homo sapiens]
[Complex:8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:202277] PIP3, PI(3,4)P2 [plasma membrane]
(input)[Reaction:1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane [Homo sapiens]
[BlackBoxEvent:1675834] PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane [Homo sapiens]
[Reaction:1676139] PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane [Mus musculus]
[Reaction:1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane [Homo sapiens]
[Reaction:1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane [Homo sapiens]
[Reaction:1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner [Homo sapiens]
[Reaction:8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2 [Homo sapiens]
(output)[Reaction:202237] Hydrolysis of PIP3 to PI(3,4)P2 [Homo sapiens]
[Reaction:1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane [Homo sapiens]
[Reaction:1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane [Homo sapiens]
[Reaction:1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane [Homo sapiens]
[Reaction:8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 [Homo sapiens]
(regulator)[PositiveRegulation:8868077] Positive regulation by 'PI(3,4)P2 [plasma membrane]'
(updatedInstance)[_UpdateTracker:9890500] Update Tracker - [SimpleEntity:202247] PI(3,4)P2 [plasma membrane] - v52:[addName]
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No pathways have been reviewed or authored by PI(3,4)P2 [plasma membrane] (202247)