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Details on Person Activation of ZAP-70

Class:IdReaction:202174
_displayNameActivation of ZAP-70
_doReleaseTRUE
_timestamp2008-06-20 09:42:48
authored[InstanceEdit:211006] Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
catalystActivity[CatalystActivity:202191] protein tyrosine kinase activity of phospho tyrosine ZAP-70 [plasma membrane]
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:202250] Garapati, P V, 2007-10-29 14:08:25
input[Complex:202345] phospho tyrosine ZAP-70 [plasma membrane] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:202361] The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes
[LiteratureReference:202253] The Syk family of protein tyrosine kinases in T-cell activation and development
modified[InstanceEdit:202491] Garapati, P V, 2007-10-30 16:01:01
[InstanceEdit:203257] Garapati, P V, 2007-11-12 15:37:54
[InstanceEdit:203950] Gopinathrao, G, 2007-11-20 16:27:22
[InstanceEdit:204115] de Bono, B, 2007-11-25 09:35:47
[InstanceEdit:212474] Garapati, P V, 2008-02-12 09:52:01
[InstanceEdit:213345] Gopinathrao, G, 2008-02-25 21:36:16
[InstanceEdit:213436] Garapati, P V, 2008-02-26 11:28:01
[InstanceEdit:214480] Garapati, P V, 2008-02-26 12:04:24
[InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActivation of ZAP-70
output[Complex:202181] Activated ZAP-70 [plasma membrane] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate2008-03-12
reviewed[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360639] R-HSA-202174.2
summation[Summation:203253] Later ZAP-70 undergoes trans-autophosphorylation at Y315 and...
(hasEvent)[Pathway:202430] Translocation of ZAP-70 to Immunological synapse [Homo sapiens]
(precedingEvent)[Reaction:202245] Phosphorylation of TBSMs in LAT [Homo sapiens]
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No pathways have been reviewed or authored by Activation of ZAP-70 (202174)