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Details on Person Caveolin-1 dissociates from eNOS:CaM:HSP90 complex

Class:IdReaction:202144
_displayNameCaveolin-1 dissociates from eNOS:CaM:HSP90 complex
_doReleaseTRUE
_timestamp2024-08-02 15:43:18
authored[InstanceEdit:202104] Hemish, J, 2007-10-19 18:00:42
catalystActivity[CatalystActivity:9911148] nitric-oxide synthase regulator activity of eNOS:Caveolin-1:CaM:HSP90 [plasma membrane]
catalystActivityReference[CatalystActivityReference:9911117] nitric-oxide synthase regulator activity of eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.
compartment[Compartment:876] plasma membrane
created[InstanceEdit:202104] Hemish, J, 2007-10-19 18:00:42
input[Complex:202130] eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] [Homo sapiens]
internalReviewed[InstanceEdit:9911325] D'Eustachio, Peter, 2024-05-28
literatureReference[LiteratureReference:202103] Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.
modified[InstanceEdit:202146] Hemish, J, 2007-10-19 18:29:27
[InstanceEdit:203590] Hemish, J, 2007-11-15 17:00:52
[InstanceEdit:204294] Gopinathrao, G, 2007-11-27 21:50:36
[InstanceEdit:212984] Gopinathrao, G, 2008-02-16 13:08:05
[InstanceEdit:213341] Gopinathrao, G, 2008-02-25 19:53:36
[InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06
[InstanceEdit:215281] Gopinathrao, G, 2008-02-28 04:43:00
[InstanceEdit:215294] Gopinathrao, G, 2008-02-28 05:36:31
[InstanceEdit:215431] Gopinathrao, G, 2008-02-28 15:47:21
[InstanceEdit:215471] Gopinathrao, G, 2008-02-28 17:53:21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9911167] D'Eustachio, Peter, 2024-05-24
[InstanceEdit:9911326] D'Eustachio, Peter, 2024-05-28
[InstanceEdit:9917335] D'Eustachio, Peter, 2024-08-02
nameCaveolin-1 dissociates from eNOS:CaM:HSP90 complex
output[EntityWithAccessionedSequence:163510] CAV1 [lipid droplet] [Homo sapiens]
[Complex:202105] eNOS:CaM:HSP90 [plasma membrane] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2008-03-12
reviewed[InstanceEdit:215470] Enikolopov, G, 2008-02-28 17:52:44
[InstanceEdit:9917333] Hill, David P, 2024-08-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359794] R-HSA-202144.3
structureModified[InstanceEdit:9911167] D'Eustachio, Peter, 2024-05-24
summation[Summation:203748] HSP90 facilitates the CaM-induced displacement of caveolin f...
(hasEvent)[Pathway:203615] eNOS activation [Homo sapiens]
[Pathway:5218920] VEGFR2 mediated vascular permeability [Homo sapiens]
(precedingEvent)[Reaction:202137] AKT1 binds eNOS complex via HSP90 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9919375] Update Tracker - [Reaction:202144] Caveolin-1 dissociates from eNOS:CaM:HSP90 complex - v90:[modifyText, removeCatalystActivity]
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