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Details on Person HSP90 binds eNOS:Caveolin-1:CaM complex

Class:IdReaction:202129
_displayNameHSP90 binds eNOS:Caveolin-1:CaM complex
_doReleaseTRUE
_timestamp2024-08-02 15:43:25
authored[InstanceEdit:202104] Hemish, J, 2007-10-19 18:00:42
catalystActivity[CatalystActivity:9911140] nitric-oxide synthase regulator activity of HSP90AA1 [cytosol]
catalystActivityReference[CatalystActivityReference:9911153] nitric-oxide synthase regulator activity of HSP90AA1 [cytosol] Dynamic activation of endothelial nitric oxide synthase by Hsp90
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:202104] Hemish, J, 2007-10-19 18:00:42
input[EntityWithAccessionedSequence:192864] HSP90AA1 [cytosol] [Homo sapiens]
[Complex:202116] eNOS:Caveolin-1:CaM [plasma membrane] [Homo sapiens]
internalReviewed[InstanceEdit:9911325] D'Eustachio, Peter, 2024-05-28
literatureReference[LiteratureReference:202143] Dynamic activation of endothelial nitric oxide synthase by Hsp90
modified[InstanceEdit:202146] Hemish, J, 2007-10-19 18:29:27
[InstanceEdit:203590] Hemish, J, 2007-11-15 17:00:52
[InstanceEdit:204294] Gopinathrao, G, 2007-11-27 21:50:36
[InstanceEdit:212984] Gopinathrao, G, 2008-02-16 13:08:05
[InstanceEdit:213341] Gopinathrao, G, 2008-02-25 19:53:36
[InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06
[InstanceEdit:215281] Gopinathrao, G, 2008-02-28 04:43:00
[InstanceEdit:215295] Gopinathrao, G, 2008-02-28 05:37:31
[InstanceEdit:215431] Gopinathrao, G, 2008-02-28 15:47:21
[InstanceEdit:215471] Gopinathrao, G, 2008-02-28 17:53:21
[InstanceEdit:534991] D'Eustachio, P, 2010-03-03
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9911167] D'Eustachio, Peter, 2024-05-24
[InstanceEdit:9911326] D'Eustachio, Peter, 2024-05-28
[InstanceEdit:9917335] D'Eustachio, Peter, 2024-08-02
nameHSP90 binds eNOS:Caveolin-1:CaM complex
output[Complex:74294] CALM1:4xCa2+ [cytosol] [Homo sapiens]
[Complex:202130] eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2008-03-12
reviewed[InstanceEdit:215470] Enikolopov, G, 2008-02-28 17:52:44
[InstanceEdit:9917333] Hill, David P, 2024-08-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358547] R-HSA-202129.3
structureModified[InstanceEdit:9911167] D'Eustachio, Peter, 2024-05-24
summation[Summation:203744] HSP90 interacts with the amino terminus of eNOS (amino acids...
(hasEvent)[Pathway:203615] eNOS activation [Homo sapiens]
[Pathway:5218920] VEGFR2 mediated vascular permeability [Homo sapiens]
(precedingEvent)[Reaction:202144] Caveolin-1 dissociates from eNOS:CaM:HSP90 complex [Homo sapiens]
[NegativePrecedingEvent:9865999] Futile Cycle: HSP90 binds eNOS:Caveolin-1:CaM complex
(updatedInstance)[_UpdateTracker:9790386] Update Tracker - [Reaction:202129] HSP90 binds eNOS:Caveolin-1:CaM complex - v33:[add_removeOutput]
[_UpdateTracker:9919512] Update Tracker - [Reaction:202129] HSP90 binds eNOS:Caveolin-1:CaM complex - v90:[removeCatalystActivity]
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No pathways have been reviewed or authored by HSP90 binds eNOS:Caveolin-1:CaM complex (202129)