Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person p-T,p-S-AKT [cytosol]

Class:IdCandidateSet:202074
_displayNamep-T,p-S-AKT [cytosol]
_timestamp2018-04-13 16:42:46
compartment[Compartment:70101] cytosol
created[InstanceEdit:202071] Jassal, B, 2007-10-18 12:38:34
hasCandidate
hasMember
modified[InstanceEdit:1474193] Orlic-Milacic, Marija, 2011-08-05
[InstanceEdit:1549533] Orlic-Milacic, Marija, 2011-08-29
[InstanceEdit:3009364] Jassal, B, 2013-02-05
[InstanceEdit:9603363] Jassal, Bijay, 2018-03-21
[InstanceEdit:9605536] Orlic-Milacic, Marija, 2018-04-13
namep-T,p-S-AKT
Active AKT
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:366744] R-HSA-202074.2
(activeUnit)[CatalystActivity:198368] protein serine/threonine kinase activity of p-T,p-S-AKT [cytosol]
(hasComponent)[Complex:198338] PIP3:PDK1:active AKT [plasma membrane] [Homo sapiens]
[Complex:389748] Akt:pCot [plasma membrane] [Homo sapiens]
(input)[Reaction:198298] AKT translocates to the nucleus [Homo sapiens]
[Reaction:199425] PHLPP dephosphorylates S473 in AKT [Homo sapiens]
[Reaction:390329] Dephosphorylation of AKT by PP2A [Homo sapiens]
(normalEntity)[EntityFunctionalStatus:2400002] gain_of_function of p-T308,S473-AKT1 E17K [cytosol]
(output)[Reaction:198270] PDPK1 phosphorylates AKT at T308 [Homo sapiens]
[Reaction:1531246] Activated AKT dissociates from PIP3:PDK1 [Homo sapiens]
(physicalEntity)[CatalystActivity:198368] protein serine/threonine kinase activity of p-T,p-S-AKT [cytosol]
(regulator)[PositiveRegulation:9762112] Positive regulation by 'p-T,p-S-AKT [cytosol]'
(updatedInstance)[_UpdateTracker:9870220] Update Tracker - [CandidateSet:202074] p-T,p-S-AKT [cytosol] - v38:[addName]
[_UpdateTracker:9878044] Update Tracker - [CandidateSet:202074] p-T,p-S-AKT [cytosol] - v44:[add_removeHasCandidate]
[_UpdateTracker:9899273] Update Tracker - [CandidateSet:202074] p-T,p-S-AKT [cytosol] - v65:[modifyName]
[Change default viewing format]
No pathways have been reviewed or authored by p-T,p-S-AKT [cytosol] (202074)
Follow Reactome