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Details on Person Actin assembly promoted by Src phosphorylation of cortactin

Class:IdReaction:201895
_displayNameActin assembly promoted by Src phosphorylation of cortactin
_doReleaseFALSE
_timestamp2016-07-15 23:49:53
authored[InstanceEdit:421399] Matthews, L, 2009-05-18 16:29:22
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:201903] Matthews, L, 2007-10-02 06:58:48
edited[InstanceEdit:421400] Matthews, L, 2009-05-18 16:34:30
figure[Figure:433025] /figures/cortactin_citation.jpg
[Figure:420603] /figures/actinnucleation.jpg
inferredFrom
input[Complex:200815] ARP2/3 complex [cytosol] [Homo sapiens]
[Polymer:201877] F-actin [cytosol] [Homo sapiens]
[Complex:201857] G-actin [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:197954] NCK1 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:419962] p-Y421,Y466,Y482-CTTN [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:201874] WIPF1 [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:201873] N-WASP [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:201893] Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation
modified[InstanceEdit:203063] Matthews, L, 2007-11-12 14:34:18
[InstanceEdit:419929] Matthews, L, 2009-05-10 20:36:17
[InstanceEdit:420602] Matthews, L, 2009-05-12 14:44:53
[InstanceEdit:421541] Matthews, L, 2009-05-18 22:48:16
[InstanceEdit:421560] Matthews, L, 2009-05-19 02:56:02
[InstanceEdit:421973] Matthews, L, 2009-05-22 17:07:30
[InstanceEdit:425528] Matthews, L, 2009-06-04
[InstanceEdit:433000] Matthews, L, 2009-08-20
[InstanceEdit:433026] Matthews, L, 2009-08-20
[InstanceEdit:433087] Matthews, L, 2009-08-21
[InstanceEdit:434569] Matthews, L, 2009-08-31
[InstanceEdit:434609] Matthews, L, 2009-09-01
[InstanceEdit:437223] Matthews, L, 2009-09-14
[InstanceEdit:437226] Matthews, L, 2009-09-14
[InstanceEdit:446734] Matthews, L, 2009-11-17
[InstanceEdit:448343] Matthews, L, 2009-11-24
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9606200] Wu, G, 2018-04-19
nameActin assembly promoted by Src phosphorylation of cortactin
Association of cortactin with:N-WASP:ARP2/3 complex
output[Complex:419945] cortactin-activated ARP2/3 complex [cytosol] [Homo sapiens]
regulatedBy[PositiveRegulation:420611] Positive regulation by 'CDC42-GTP [cytosol]'
[PositiveRegulation:420613] Positive regulation by 'PI(4,5)P2 [plasma membrane]'
reviewed[InstanceEdit:434566] Weed, S, Ammer, AG, 2009-08-31
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8906619] R-HSA-201895.1
summation[Summation:201887] c-Src mediated reorganization of the actin cytoskeleton play...
(hasEvent)[Pathway:419989] Actin assembly [Homo sapiens]
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No pathways have been reviewed or authored by Actin assembly promoted by Src phosphorylation of cortactin (201895)