Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person UniProt:O95813 CER1

Class:IdReferenceGeneProduct:201815
_chainChangeLogsignal peptide:1-17 added on Fri February 6 2015;chain:18-267 added on Fri February 6 2015
_displayNameUniProt:O95813 CER1
_timestamp2024-11-03 19:45:02
chainsignal peptide:1-17
chain:18-267
checksumC9FB048CD8558ED7
commentFUNCTION Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak (By similarity).SUBUNIT Forms monomers and predominantly dimers.SUBCELLULAR LOCATION N-glycosylated.SIMILARITY Belongs to the DAN family.SEQUENCE CAUTION Truncated C-terminus.
created[InstanceEdit:201812] Jassal, B, 2007-09-25 08:39:03
descriptionrecommendedName: Cerberus alternativeName: Cerberus-related protein alternativeName: DAN domain family member 4
geneNameCER1
DAND4
identifierO95813
isSequenceChangedFALSE
keywordCytokine
Direct protein sequencing
Disulfide bond
Glycoprotein
Proteomics identification
Reference proteome
Secreted
Signal
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameCER1
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9003433] ENSEMBL:ENSG00000147869 CER1 [Homo sapiens]
secondaryIdentifierCER1_HUMAN
Q6ISJ1
Q6ISJ6
Q6ISQ2
Q6ISS1
sequenceLength267
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:201831] CER1 [extracellular region] [Homo sapiens]
[EntityWithAccessionedSequence:9921118] CER1 [exocytic vesicle] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:O95813 CER1 (201815)