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Details on Person Inactive catalytic PP2B is activated by the binding of calmodulin

Class:Id	Reaction:201783
_displayName	Inactive catalytic PP2B is activated by the binding of calmodulin
_doRelease	TRUE
_timestamp	2008-12-03 09:55:33
authored	[InstanceEdit:112007] Le Novere, N, Jassal, B, 2004-03-31 12:22:05
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:201796] Jassal, Bijay, 2007-09-20
edited	[InstanceEdit:379927] Jassal, Bijay, 2008-11-06
inferredFrom	[Reaction:375176] Inactive catalytic PP2B is activated by the binding of calmodulin [Bos taurus]
input	[Complex:74294] CALM1:4xCa2+ [cytosol] [Homo sapiens] [Complex:201779] PP2B catalytic (Fe3+, Zn2+) [cytosol] [Homo sapiens]
modified	[InstanceEdit:375190] Jassal, B, 2008-08-12 10:20:08 [InstanceEdit:379936] Jassal, Bijay, 2008-11-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Inactive catalytic PP2B is activated by the binding of calmodulin
output	[Complex:201762] PPP3CA,B,C:Fe3+:Zn2+:4xCa2+:CaM [cytosol] [Homo sapiens]
precedingEvent	[Reaction:74448] Calcium binds calmodulin [Homo sapiens] [Reaction:139854] IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol [Homo sapiens] [Reaction:434798] CRAC translocates calcium from the extracellular region to the cytosol [Homo sapiens] [Reaction:2089943] TRPC1 translocates calcium from the extracellular region to the cytosol [Homo sapiens] [Reaction:9700718] T-type VDCC transports Ca2+ from extracellular region to cytosol [Homo sapiens] [Reaction:9855089] PIEZO1 trimer passively transports cations across the plasma membrane according to their electrochemical gradients [Homo sapiens] [Reaction:169683] IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol [Homo sapiens] [Reaction:9858800] TRPV4 tetramer:CALM1:Ca2+ transports calcium ions (Ca2+) from the extracellular region to the cytosol [Homo sapiens]
releaseDate	2008-12-17
reviewed	[InstanceEdit:379937] Castagnoli, L, 2008-11-06 12:55:54
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:387562] R-HSA-201783.2
summation	[Summation:201793] PP2B (calcineurin) is a calcium-dependent, calmodulin-stimul...
(hasEvent)	[Pathway:180024] DARPP-32 events [Homo sapiens]
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