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Details on Person CSNK2-mediated phosphorylation of DVL

Class:Id	Reaction:201717
_displayName	CSNK2-mediated phosphorylation of DVL
_doRelease	TRUE
_timestamp	2014-11-20 02:39:12
authored	[InstanceEdit:4415000] Rothfels, K, 2013-08-23
catalystActivity	[CatalystActivity:201699] protein serine/threonine kinase activity of Casein kinase II [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:201703] Matthews, L, 2007-09-10 21:56:08
edited	[InstanceEdit:201675] Matthews, L, 2007-09-04 11:49:29 [InstanceEdit:4655138] Gillespie, ME, 2013-10-02
input	[DefinedSet:201725] DVL [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:3772336] Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis [LiteratureReference:3772361] Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases [LiteratureReference:3772328] Casein kinase 2 associates with and phosphorylates dishevelled [LiteratureReference:3772372] The dishevelled protein is modified by wingless signaling in Drosophila [LiteratureReference:3772345] Human dishevelled genes constitute a DHR-containing multigene family
modified	[InstanceEdit:3772423] Rothfels, K, 2013-06-24 [InstanceEdit:4416357] Rothfels, K, 2013-08-25 [InstanceEdit:4518430] Rothfels, K, 2013-09-03 [InstanceEdit:4655144] Rothfels, K, 2013-10-02 [InstanceEdit:5097254] Rothfels, K, 2013-11-11 [InstanceEdit:5146674] Rothfels, K, 2013-11-18 [InstanceEdit:5228703] Rothfels, K, 2014-01-14 [InstanceEdit:5251582] Rothfels, K, 2014-02-04 [InstanceEdit:5323561] Rothfels, K, 2014-02-15 [InstanceEdit:5576906] Rothfels, Karen, 2014-05-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CSNK2-mediated phosphorylation of DVL
output	[DefinedSet:201689] p-DVL [cytosol] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol]
releaseDate	2014-03-12
reviewed	[InstanceEdit:5251465] Rajakulendran, Nishani, 2014-01-22 [InstanceEdit:5323527] van Amerongen, R, 2014-02-14 [InstanceEdit:5368564] Kikuchi, Akira, 2014-04-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:5644493] R-HSA-201717.2
summation	[Summation:201682] DVL proteins from Drosophila, Xenopus, mouse and human cells...
(hasEvent)	[Pathway:201688] WNT mediated activation of DVL [Homo sapiens]
(precedingEvent)	[Reaction:3772435] WNT signaling stimulates CSNK1-dependent phosphorylation of DVL [Homo sapiens]
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