Query author contributions in Reactome Reactome depends on collaboration between our curation team and outside experts to
assemble and peer-review its pathway modules. The integration of ORCID within Reactome
enables us to meet a key challenge with authoring, curating and reviewing biological
information by incentivizing and crediting the external experts that contribute their
expertise and time to the Reactome curation process. More information is available at
ORCID and Reactome .
If you have an ORCID ID that is not listed on this page, please
forward this information to us and we will update your Reactome pathway records.
Details on Person Beta-catenin translocates to the nucleus
Class:Id BlackBoxEvent:201669 _displayName Beta-catenin translocates to the nucleus _doRelease TRUE _timestamp 2018-05-07 17:36:00 authored [InstanceEdit:4415000] Rothfels, K, 2013-08-23 compartment [Compartment:70101] cytosol [Compartment:7660] nucleoplasm created [InstanceEdit:201703] Matthews, L, 2007-09-10 21:56:08 edited [InstanceEdit:201675] Matthews, L, 2007-09-04 11:49:29 [InstanceEdit:4655138] Gillespie, ME, 2013-10-02 goBiologicalProcess [GO_BiologicalProcess:436450] regulation of canonical Wnt signaling pathway input [EntityWithAccessionedSequence:448839] CTNNB1 [cytosol] [Homo sapiens] literatureReference [LiteratureReference:1458900] Wnt/beta-catenin signaling: components, mechanisms, and diseases [LiteratureReference:3238089] The way Wnt works: Components and mechanism [LiteratureReference:3769242] Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin [LiteratureReference:3769275] beta-catenin can be transported into the nucleus in a Ran-unassisted manner [LiteratureReference:3769225] Dominant-negative mutants of importin-beta block multiple pathways of import and export through the nuclear pore complex [LiteratureReference:3769228] Evolutionary specialization of the nuclear targeting apparatus [LiteratureReference:208063] Pygopus and Legless target Armadillo/beta-catenin to the nucleus to enable its transcriptional co-activator function [LiteratureReference:3769212] Armadillo nuclear import is regulated by cytoplasmic anchor Axin and nuclear anchor dTCF/Pan [LiteratureReference:208284] Nucleo-cytoplasmic distribution of beta-catenin is regulated by retention [LiteratureReference:3769261] The ins and outs of APC and beta-catenin nuclear transport [LiteratureReference:3769243] Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin [LiteratureReference:3769248] Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling [LiteratureReference:3772343] FoxM1 promotes ?-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis modified [InstanceEdit:201937] Matthews, L, 2007-10-09 13:39:40 [InstanceEdit:388403] Matthews, L, 2008-12-05 13:20:23 [InstanceEdit:3322439] Rothfels, K, 2013-05-03 [InstanceEdit:3451177] Rothfels, K, 2013-05-16 [InstanceEdit:3769405] Rothfels, K, 2013-06-19 [InstanceEdit:3772444] Rothfels, K, 2013-06-24 [InstanceEdit:4416357] Rothfels, K, 2013-08-25 [InstanceEdit:4518428] Rothfels, K, 2013-09-03 [InstanceEdit:4641287] Rothfels, K, 2013-09-27 [InstanceEdit:4655191] Rothfels, K, 2013-10-02 [InstanceEdit:5097338] Rothfels, K, 2013-11-11 [InstanceEdit:5146689] Rothfels, K, 2013-11-18 [InstanceEdit:5228763] Rothfels, K, 2014-01-14 [InstanceEdit:5251657] Rothfels, K, 2014-02-04 [InstanceEdit:5323638] Rothfels, K, 2014-02-15 [InstanceEdit:5576959] Rothfels, Karen, 2014-05-27 [InstanceEdit:6782916] Rothfels, Karen, 2015-06-09 [InstanceEdit:8854806] Rothfels, Karen, 2016-01-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name Beta-catenin translocates to the nucleus output [EntityWithAccessionedSequence:3451168] CTNNB1 [nucleoplasm] [Homo sapiens] precedingEvent
releaseDate 2014-03-12 reviewed [InstanceEdit:5251465] Rajakulendran, Nishani, 2014-01-22 [InstanceEdit:5323527] van Amerongen, R, 2014-02-14 [InstanceEdit:5368564] Kikuchi, Akira, 2014-04-22 reviewStatus [ReviewStatus:9821382] five stars species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:5645115] R-HSA-201669.4 summation [Summation:3769374] Although it is well established that stabilized beta-catenin... (hasEvent) [Pathway:201681] TCF dependent signaling in response to WNT [Homo sapiens] (precedingEvent) [Pathway:201722] Formation of the beta-catenin:TCF transactivating complex [Homo sapiens] [Reaction:201731] TCF-4:beta-catenin complex formation [Homo sapiens] [Reaction:3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF [Homo sapiens] [Reaction:3769383] CBY1 binds beta-catenin [Homo sapiens] [Reaction:3772430] CTNNBIP1 binds beta-catenin [Homo sapiens] [Reaction:5368580] CHD8 binds beta-catenin to negatively regulate WNT-dependent gene expression [Homo sapiens] [Reaction:5626938] Beta-catenin binds SOX proteins [Homo sapiens] [Reaction:9754191] LEF1 or TCF7 (TCF1), CTNNB1, and TBPL2 (TRF3) bind the TBXT (T, Brachyury) gene [Homo sapiens] [Reaction:9754480] p-2S-SMAD2,3:SMAD4, CTNNB1, and TBPL2 bind FOXH1:SMAD3:EOMES gene [Homo sapiens] [Reaction:9756724] p-2S-SMAD2,3:TRIM33, p-2S-SMAD2,3:SMAD4, CTNNB1, EOMES, and TBPL2 bind FOXH1:MIXL1 gene [Homo sapiens]
[Change default viewing format]
List...
Protein identifiers
ChEBI identifiers
KEGG COMPOUND identifiers
No pathways have been reviewed or authored by Beta-catenin translocates to the nucleus (201669)
