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Details on Person Caspase-mediated cleavage of Desmoglein 3

Class:Id	Reaction:201631
_displayName	Caspase-mediated cleavage of Desmoglein 3
_doRelease	TRUE
_timestamp	2017-11-24 15:42:01
authored	[InstanceEdit:201620] Schulze-Osthoff, K, 2007-09-03 07:52:18
catalystActivity	[CatalystActivity:114327] cysteine-type endopeptidase activity of Caspase-3 [cytosol]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:201633] Matthews, L, 2007-09-03 08:38:43
edited	[InstanceEdit:201589] Matthews, L, 2007-09-03 07:38:20 [InstanceEdit:201989] Matthews, L, 2007-10-09 13:44:38 [InstanceEdit:202801] Matthews, L, 2007-11-11 23:40:56
input	[EntityWithAccessionedSequence:201590] DSG3 [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:202796] The fate of desmosomal proteins in apoptotic cells
modified	[InstanceEdit:202798] Matthews, L, 2007-11-12 09:45:38 [InstanceEdit:202978] Matthews, L, 2007-11-12 13:46:00 [InstanceEdit:204062] Matthews, L, 2007-11-23 00:36:25 [InstanceEdit:351919] Matthews, L, 2008-05-28 22:38:42 [InstanceEdit:352465] Matthews, L, 2008-06-03 00:23:29 [InstanceEdit:352491] Matthews, L, 2008-06-03 01:13:58 [InstanceEdit:353640] Matthews, L, 2008-06-13 11:27:03 [InstanceEdit:500667] Matthews, L, 2010-02-04 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9029450] Orlic-Milacic, Marija, 2017-11-17 [InstanceEdit:9029992] Orlic-Milacic, Marija, 2017-11-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Caspase-mediated cleavage of Desmoglein 3
output	[EntityWithAccessionedSequence:202803] DSG3(50-781) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:202797] DSG3(782-999) [cytosol] [Homo sapiens]
precedingEvent	[Reaction:114252] Cleavage of Procaspase-3 by the apoptosome [Homo sapiens] [Reaction:114259] Cleavage of Procaspase‑9 to caspase‑9 [Homo sapiens] [Reaction:114419] Dissociation of Caspase-3 from DIABLO:XIAP:Caspase-3 [Homo sapiens] [Reaction:114306] SMAC binds XIAP:Caspase-3 [Homo sapiens] [Reaction:418845] Activation of caspase-3 [Homo sapiens] [Reaction:373700] Caspase-9 binds DCC:DIP13alpha complex [Homo sapiens]
releaseDate	2006-08-02
reviewed	[InstanceEdit:350641] Ranganathan, S, 2008-06-11 19:13:33
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361398] R-HSA-201631.4
summation	[Summation:202800] In epithelial cells, desmosomes are anchoring junctions that...
(hasEvent)	[Pathway:351906] Apoptotic cleavage of cell adhesion proteins [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9779713] Update Tracker - [Reaction:201631] Caspase-mediated cleavage of Desmoglein 3 - v64:[add_removeCatalystActivity] [_UpdateTracker:9791223] Update Tracker - [Reaction:201631] Caspase-mediated cleavage of Desmoglein 3 - v32:[add_removeCatalystActivity] [_UpdateTracker:9791842] Update Tracker - [Reaction:201631] Caspase-mediated cleavage of Desmoglein 3 - v25:[modifyText]
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