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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person PTK2 [cytosol]

Class:IdEntityWithAccessionedSequence:201621
_displayNamePTK2 [cytosol]
_timestamp2016-05-20 18:06:24
compartment[Compartment:70101] cytosol
created[InstanceEdit:201610] Matthews, L, 2007-09-03 08:36:41
endCoordinate1052
modified[InstanceEdit:392341] Williams, MG, 2009-03-03 09:54:46
[InstanceEdit:939908] Jupe, S, 2010-09-02
[InstanceEdit:3008640] D'Eustachio, P, 2013-02-01
[InstanceEdit:3322333] Wu, G, 2013-05-03
[InstanceEdit:3322334] Wu, G, 2013-05-03
[InstanceEdit:3448660] Wu, G, 2013-05-16
[InstanceEdit:5218752] Garapati, P V, 2013-12-19
[InstanceEdit:5660684] Jassal, Bijay, 2015-01-05
[InstanceEdit:8874091] Orlic-Milacic, Marija, 2016-05-20
namePTK2
FAK1
FADK1
FAK
Focal adhesion kinase 1
referenceEntity[ReferenceGeneProduct:54648] UniProt:Q05397 PTK2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:364759] R-HSA-201621.2
startCoordinate2
(activeUnit)[CatalystActivity:354119] protein tyrosine kinase activity of Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane]
[CatalystActivity:418875] protein tyrosine kinase activity of NTN1:DCC oligomer:PTK2 [plasma membrane]
[CatalystActivity:3928574] protein tyrosine kinase activity of EFNBs:p-EPHBs:PTK2 [plasma membrane]
[CatalystActivity:5218644] protein tyrosine kinase activity of VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane]
[CatalystActivity:8874093] protein tyrosine kinase activity of HGF:p-4Y-MET dimer:PTK2 [plasma membrane]
[CatalystActivity:9625454] protein tyrosine kinase activity of EGF-like ligands:p-6Y EGFR:PTK2 [plasma membrane]
(hasCandidate)[CandidateSet:548936] SRC-1, PTK2 [cytosol] [Homo sapiens]
(hasComponent)[Complex:354103] Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] [Homo sapiens]
[Complex:373662] NTN1:DCC oligomer:PTK2 [plasma membrane] [Homo sapiens]
[Complex:376040] p-T2796-TRIO:FADK1 [cytosol] [Homo sapiens]
[Complex:398222] Integrin beta-1:FADK 1 [plasma membrane] [Homo sapiens]
[Complex:3928544] EFNBs:p-EPHBs:PTK2 [plasma membrane] [Homo sapiens]
[Complex:4420141] VEGFA:p-6Y-VEGFR2:p-SHB:PTK2 [plasma membrane] [Homo sapiens]
[Complex:8874088] HGF:p-4Y-MET dimer:PTK2 [plasma membrane] [Homo sapiens]
[Complex:9625453] EGF-like ligands:p-6Y EGFR:PTK2 [plasma membrane] [Homo sapiens]
(hasMember)[DefinedSet:201570] Caspase targets [cytosol] [Homo sapiens]
[CandidateSet:2197681] Src-kinases [cytosol] [Homo sapiens]
(input)[Reaction:201634] Caspase-mediated cleavage of FADK 1 [Homo sapiens]
[Reaction:354066] Translocation of PTK2 to Focal complexes [Homo sapiens]
[Reaction:373720] FADK1 interaction with DCC [Homo sapiens]
[Reaction:376136] Phosphorylation of Trio by FAK [Homo sapiens]
[Reaction:391865] Recruitment of FAK to NCAM1:Fyn in lipid rafts [Homo sapiens]
[Reaction:392333] FADK 1 kinase binds to inactive integrin beta1 subunit [Homo sapiens]
[Reaction:3928588] EPHBs binds PTK2 [Homo sapiens]
[Reaction:4420083] PTK2 binds p-S-SHB and is recruited to p-6Y-VEGFR2 [Homo sapiens]
[Reaction:8874079] PTK2 binds activated MET [Homo sapiens]
[Reaction:9625482] PTK2 binds activated EGFR [Homo sapiens]
List all 11 refering instances
(physicalEntity)[CatalystActivity:376142] protein tyrosine kinase activity of PTK2 [cytosol]
(updatedInstance)[_UpdateTracker:9868002] Update Tracker - [EntityWithAccessionedSequence:201621] PTK2 [cytosol] - v28:[modifyEndCoordinate, modifyStartCoordinate]
[_UpdateTracker:9869590] Update Tracker - [EntityWithAccessionedSequence:201621] PTK2 [cytosol] - v34:[modifyName]
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No pathways have been reviewed or authored by PTK2 [cytosol] (201621)
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