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Details on Person PDK2 phosphorylates AKT at T308 and S473

Class:Id	Reaction:201527
_displayName	PDK2 phosphorylates AKT at T308 and S473
_timestamp	2016-12-01 00:31:50
catalystActivity	[CatalystActivity:201505] protein serine/threonine kinase activity of PDPK2 [cytosol]
compartment	[Compartment:947587] cytoplasmic side of plasma membrane
created	[InstanceEdit:201539] Jassal, B, 2007-08-21 12:50:53
input	[Complex:198618] PIP3:PDK1:Phospho-AKT [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:199373] Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
modified	[InstanceEdit:201560] Jassal, B, 2007-08-22 08:37:48 [InstanceEdit:392448] Jupe, S, 2009-03-04 10:19:39 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:8949915] D'Eustachio, Peter, 2016-12-01
name	PDK2 phosphorylates AKT at T308 and S473
output	[Complex:198338] PIP3:PDK1:active AKT [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:198270] PDPK1 phosphorylates AKT at T308 [Homo sapiens] [Reaction:2317314] AKT binds PDPK1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8906068] R-HSA-201527.1
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No pathways have been reviewed or authored by PDK2 phosphorylates AKT at T308 and S473 (201527)