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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Active ALK recruits PI3K

Class:IdBlackBoxEvent:201515
_displayNameActive ALK recruits PI3K
_doReleaseTRUE
_timestamp2023-11-09 18:37:15
authored[InstanceEdit:201559] Jassal, B, 2007-08-21 12:55:28
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:201539] Jassal, B, 2007-08-21 12:50:53
edited[InstanceEdit:201559] Jassal, B, 2007-08-21 12:55:28
input[Complex:74693] PI3K [cytosol] [Homo sapiens]
[CandidateSet:9850879] Active ALK dimer [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:9699737] Nucleophosmin-anaplastic lymphoma kinase associated with anaplastic large-cell lymphoma activates the phosphatidylinositol 3-kinase/Akt antiapoptotic signaling pathway
[LiteratureReference:201541] Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis
[LiteratureReference:9667881] The anaplastic lymphoma kinase in the pathogenesis of cancer
[LiteratureReference:201494] Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin
[LiteratureReference:9667900] Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types
modified[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8949915] D'Eustachio, Peter, 2016-12-01
[InstanceEdit:9700211] Rothfels, Karen, 2020-09-14
[InstanceEdit:9729590] Rothfels, Karen, 2021-04-30
[InstanceEdit:9729893] Rothfels, Karen, 2021-05-04
[InstanceEdit:9730936] Jassal, Bijay, 2021-05-12
[InstanceEdit:9731181] Rothfels, Karen, 2021-05-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9850956] Rothfels, Karen, 2023-10-12
[InstanceEdit:9853043] Rothfels, Karen, 2023-11-09
nameActive ALK recruits PI3K
output[Complex:9699995] Active ALK:PI3K [plasma membrane] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821384] two stars
releaseDate2021-06-09
reviewed[InstanceEdit:9729891] Inghirami, Giorgio, 2021-05-04
[InstanceEdit:9852935] Turner, Suzanne, 2023-11-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8929765] R-HSA-201515.3
structureModified[InstanceEdit:9850956] Rothfels, Karen, 2023-10-12
summation[Summation:201538] Activated ALK in the form of NPM-ALK recruits PI3K. Binding ...
(hasEvent)[Pathway:201556] Signaling by ALK [Homo sapiens]
(normalReaction)[Reaction:9712083] ALK mutants bind PI3KCA [Homo sapiens]
(precedingEvent)[Reaction:201498] ALK phosphorylates PI3K via p85 subunit [Homo sapiens]
[Reaction:201510] PI3K synthesizes PIP3 downstream of ALK [Homo sapiens]
(updatedInstance)[_UpdateTracker:9853263] Update Tracker - [BlackBoxEvent:201515] Active ALK recruits PI3K - v87:[addLiteratureReference, add_removeInput, modifyText]
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No pathways have been reviewed or authored by Active ALK recruits PI3K (201515)
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