Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Binding of PTN is believed to induce ALK receptor dimerizati...

Class:IdSummation:201493
_displayNameBinding of PTN is believed to induce ALK receptor dimerizati...
_timestamp2020-09-29 14:53:36
created[InstanceEdit:201539] Jassal, B, 2007-08-21 12:50:53
modified[InstanceEdit:9700212] Rothfels, Karen, 2020-09-14
[InstanceEdit:9702115] Rothfels, Karen, 2020-09-29
textBinding of PTN is believed to induce ALK receptor dimerization, similar to other receptor tyrosine kinases (reviewed in Roskoski, 2013; Della Corte et al, 2018). Consistent with this, studies in rat with enforced dimerization of ALK lead to receptor activation, downstream signaling and neurite outgrowth in PC12 cells (Gouzi et al, 2005).
(summation)[Reaction:201519] ALK:PTN dimerization [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Binding of PTN is believed to induce ALK receptor dimerizati... (201493)