Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Phospho-R-Smad1/5/8 dissociates from the receptor complex

Class:IdReaction:201453
_displayNamePhospho-R-Smad1/5/8 dissociates from the receptor complex
_doReleaseTRUE
_timestamp2016-11-10 00:55:17
authored[InstanceEdit:202631] Huminiecki, L, Moustakas, A, 2007-11-07 10:22:00
compartment[Compartment:17941] early endosome
created[InstanceEdit:201460] Jassal, B, 2007-08-13 08:42:05
input[Complex:201467] BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] [Homo sapiens]
literatureReference[LiteratureReference:202645] Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways
[LiteratureReference:202605] The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase
[LiteratureReference:201651] Endofin acts as a Smad anchor for receptor activation in BMP signaling
modified[InstanceEdit:201652] Jassal, B, 2007-09-03 13:27:21
[InstanceEdit:202635] Jassal, B, 2007-11-07 13:11:04
[InstanceEdit:203121] Jassal, B, 2007-11-12 14:50:39
[InstanceEdit:203414] Jassal, B, 2007-11-13 09:46:28
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
namePhospho-R-Smad1/5/8 dissociates from the receptor complex
output[Complex:201647] BMP:p-BMPR:Endofin [early endosome membrane] [Homo sapiens]
[DefinedSet:201482] p-2S-SMAD1/5/8 [cytosol] [Homo sapiens]
precedingEvent
releaseDate2005-09-26
reviewed[InstanceEdit:203122] Heldin, CH, 2007-11-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361509] R-HSA-201453.3
summation[Summation:176005] Upon phosphorylation of the R-SMAD (SMAD2/3), the conformati...
(hasEvent)[Pathway:201451] Signaling by BMP [Homo sapiens]
(precedingEvent)[Reaction:201422] Phospho-R-Smad1/5/8 forms a complex with Co-Smad [Homo sapiens]
[Reaction:202626] I-Smad competes with Co-Smad for R-Smad1/5/8 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9787043] Update Tracker - [Reaction:201453] Phospho-R-Smad1/5/8 dissociates from the receptor complex - v46:[modifyText]
[_UpdateTracker:9788530] Update Tracker - [Reaction:201453] Phospho-R-Smad1/5/8 dissociates from the receptor complex - v41:[modifyText]
[_UpdateTracker:9789317] Update Tracker - [Reaction:201453] Phospho-R-Smad1/5/8 dissociates from the receptor complex - v38:[modifyText]
[Change default viewing format]
No pathways have been reviewed or authored by Phospho-R-Smad1/5/8 dissociates from the receptor complex (201453)