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Details on Person Type II receptor phosphorylates type I receptor

Class:Id	Reaction:201443
_displayName	Type II receptor phosphorylates type I receptor
_doRelease	TRUE
_timestamp	2016-11-10 00:56:51
authored	[InstanceEdit:202631] Huminiecki, L, Moustakas, A, 2007-11-07 10:22:00
catalystActivity	[CatalystActivity:201455] activin receptor activity, type II of BMP:BMPRII:BMPRI [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:201460] Jassal, B, 2007-08-13 08:42:05
input	[Complex:201459] BMP:BMPRII:BMPRI [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:202602] Human type II receptor for bone morphogenic proteins (BMPs): extension of the two-kinase receptor model to the BMPs [LiteratureReference:202608] Cloning and characterization of a human type II receptor for bone morphogenetic proteins
modified	[InstanceEdit:202635] Jassal, B, 2007-11-07 13:11:04 [InstanceEdit:203121] Jassal, B, 2007-11-12 14:50:39 [InstanceEdit:203414] Jassal, B, 2007-11-13 09:46:28 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Type II receptor phosphorylates type I receptor
output	[Complex:201426] BMP:BMPRII:p-4S-BMPRI [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:201457] BMP2 binds to the receptor complex [Homo sapiens] [Reaction:202604] Formation of a heteromeric BMP receptor complex [Homo sapiens]
releaseDate	2005-09-26
reviewed	[InstanceEdit:203122] Heldin, CH, 2007-11-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360341] R-HSA-201443.3
summation	[Summation:201449] Formation of the hetero-tetrameric BMP2:receptor complex ind...
(hasEvent)	[Pathway:201451] Signaling by BMP [Homo sapiens]
(precedingEvent)	[Reaction:201648] An anchoring protein, Endofin, recruits R-Smad1/5/8 [Homo sapiens] [Reaction:201821] I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated [Homo sapiens]
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