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Details on Person Phospho-R-Smad1/5/8 forms a complex with Co-Smad

Class:Id	Reaction:201422
_displayName	Phospho-R-Smad1/5/8 forms a complex with Co-Smad
_doRelease	TRUE
_timestamp	2016-11-10 00:56:32
authored	[InstanceEdit:202631] Huminiecki, L, Moustakas, A, 2007-11-07 10:22:00
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:201460] Jassal, B, 2007-08-13 08:42:05
input	[DefinedSet:201482] p-2S-SMAD1/5/8 [cytosol] [Homo sapiens] [DefinedSet:201482] p-2S-SMAD1/5/8 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:170862] SMAD4 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:202645] Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways [LiteratureReference:202606] Structural basis of Smad1 activation by receptor kinase phosphorylation
modified	[InstanceEdit:202635] Jassal, B, 2007-11-07 13:11:04 [InstanceEdit:203064] Jassal, B, 2007-11-12 14:34:26 [InstanceEdit:203121] Jassal, B, 2007-11-12 14:50:39 [InstanceEdit:203414] Jassal, B, 2007-11-13 09:46:28 [InstanceEdit:8877932] Orlic-Milacic, Marija, 2016-06-28 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phospho-R-Smad1/5/8 forms a complex with Co-Smad
output	[Complex:201419] p-2S-SMAD1/5/8:SMAD4 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:201453] Phospho-R-Smad1/5/8 dissociates from the receptor complex [Homo sapiens] [Reaction:201476] Activated type I receptor phosphorylates R-Smad1/5/8 directly [Homo sapiens]
releaseDate	2005-09-26
reviewed	[InstanceEdit:203122] Heldin, CH, 2007-11-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:360266] R-HSA-201422.4
summation	[Summation:176014] The phosphorylated C-terminal tail of R-SMAD induces a confo...
(hasEvent)	[Pathway:201451] Signaling by BMP [Homo sapiens]
(precedingEvent)	[Reaction:201472] The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9775701] Update Tracker - [Reaction:201422] Phospho-R-Smad1/5/8 forms a complex with Co-Smad - v78:[modifyText] [_UpdateTracker:9787926] Update Tracker - [Reaction:201422] Phospho-R-Smad1/5/8 forms a complex with Co-Smad - v44:[modifyText] [_UpdateTracker:9788657] Update Tracker - [Reaction:201422] Phospho-R-Smad1/5/8 forms a complex with Co-Smad - v41:[modifyText] [_UpdateTracker:9789512] Update Tracker - [Reaction:201422] Phospho-R-Smad1/5/8 forms a complex with Co-Smad - v38:[modifyText]
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