Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person The phosphorylated-r-SMAD1/5/8:Co-SMAD complex rapidly trans...
| Class:Id | Summation:201421 |
|---|---|
| _displayName | The phosphorylated-r-SMAD1/5/8:Co-SMAD complex rapidly trans... |
| _timestamp | 2007-11-12 14:35:22 |
| created | [InstanceEdit:201460] Jassal, B, 2007-08-13 08:42:05 |
| modified | [InstanceEdit:203064] Jassal, B, 2007-11-12 14:34:26 |
| text | The phosphorylated-r-SMAD1/5/8:Co-SMAD complex rapidly translocates to the nucleus where it binds directly to DNA and interacts with a plethora of transcription co-factors. Regulation of target gene expression can be either positive or negative. A classic example of a target gene of the pathway are the genes encoding for i-SMADs. Thus, BMP2/SMAD signalling induces the expression of the negative regulators of the pathway (a negative feedback loop). |
| (summation) | [Reaction:201472] The phospho-R-Smad1/5/8:Co-Smad transfers to the nucleus [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The phosphorylated-r-SMAD1/5/8:Co-SMAD complex rapidly trans... (201421)
