Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person Autocatalytic phosphorylation of FGFR4 Y367C mutant

Class:Id	Reaction:2012087
_displayName	Autocatalytic phosphorylation of FGFR4 Y367C mutant
_doRelease	TRUE
_timestamp	2014-12-03 20:52:27
authored	[InstanceEdit:2105031] Rothfels, K, 2012-02-09
catalystActivity	[CatalystActivity:2012069] protein tyrosine kinase activity of FGFR4 Y367C mutant dimer [plasma membrane]
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:2012085] Rothfels, K, 2011-11-22
disease	[Disease:1500576] breast cancer [Disease:1500689] cancer
edited	[InstanceEdit:2252592] Rothfels, K, 2012-05-16
entityFunctionalStatus	[EntityFunctionalStatus:5654466] gain_of_function of FGFR4 Y367C mutant dimer [plasma membrane]
input	[Complex:2011955] FGFR4 Y367C mutant dimer [plasma membrane] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
isChimeric	FALSE
literatureReference	[LiteratureReference:2011956] The FGFR4 Y367C mutant is a dominant oncogene in MDA-MB453 breast cancer cells
modified	[InstanceEdit:2023468] Rothfels, K, 2011-12-07 [InstanceEdit:2033504] Rothfels, K, 2012-01-09 [InstanceEdit:2045089] Rothfels, K, 2012-01-10 [InstanceEdit:2046322] Rothfels, K, 2012-01-11 [InstanceEdit:2085561] Rothfels, K, 2012-02-03 [InstanceEdit:2105600] Rothfels, K, 2012-02-10 [InstanceEdit:2123530] Rothfels, K, 2012-02-14 [InstanceEdit:2156369] Rothfels, K, 2012-02-28 [InstanceEdit:2248846] Rothfels, K, 2012-05-15 [InstanceEdit:2275109] Rothfels, K, 2012-05-25 [InstanceEdit:5654467] Rothfels, Karen, 2014-12-03 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Autocatalytic phosphorylation of FGFR4 Y367C mutant
normalReaction	[Reaction:190326] Autocatalytic phosphorylation of FGFR4 [Homo sapiens]
output	[Complex:2011990] Activated FGFR4 Y367C mutant [plasma membrane] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:2012086] Constitutive dimerization of FGFR4 Y367C mutant [Homo sapiens]
releaseDate	2012-06-12
reviewed	[InstanceEdit:2248845] Ezzat, S, 2012-05-15
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2295199] R-HSA-2012087.2
summation	[Summation:2046321] Expression of the FGFR4 Y367C mutant in MDA-MB453 breast can...
(hasEvent)	[Pathway:1839128] FGFR4 mutant receptor activation [Homo sapiens]
[Change default viewing format]

No pathways have been reviewed or authored by Autocatalytic phosphorylation of FGFR4 Y367C mutant (2012087)