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Details on Person Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome

Class:IdLiteratureReference:2012014
_displayNameLoss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome
_timestamp2011-11-22 14:55:28
author[Person:2011812] Yu, K
[Person:2011600] Herr, AB
[Person:184486] Waksman, G
[Person:190249] Ornitz, DM
created[InstanceEdit:2012015] Rothfels, K, 2011-11-22
journalProc Natl Acad Sci U S A
pages14536-41
pubMedIdentifier11121055
titleLoss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome
volume97
year2000
(literatureReference)[DefinedSet:2065925] FGFR2b mutant-binding FGFs [extracellular region] [Homo sapiens]
[Reaction:2012074] FGFR3c P250R mutant binds to ligand with enhanced affinity [Homo sapiens]
[Reaction:2023451] FGFR1c P252X mutants bind ligand with enhanced affinity [Homo sapiens]
[Reaction:2033472] FGFR2c mutants bind an expanded range of ligands [Homo sapiens]
[Reaction:2033474] FGFR2b mutants bind an expanded range of ligands [Homo sapiens]
[Pathway:2033519] Activated point mutants of FGFR2 [Homo sapiens]
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