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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person FGFR1 R576W [plasma membrane]

Class:IdEntityWithAccessionedSequence:2011844
_displayNameFGFR1 R576W [plasma membrane]
_timestamp2025-07-30 21:08:27
compartment[Compartment:876] plasma membrane
created[InstanceEdit:2011843] Rothfels, K, 2011-11-22
crossReference[DatabaseIdentifier:2023324] COSMIC:COSV58339211
disease[Disease:1500689] cancer
[Disease:1247632] glioblastoma
endCoordinate822
hasModifiedResidue[ReplacedResidue:2011842] L-arginine 576 replaced with L-tryptophan
literatureReference[LiteratureReference:1614269] Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas
modified[InstanceEdit:2023365] Rothfels, K, 2011-12-07
[InstanceEdit:5649524] Rothfels, Karen, 2014-11-20
[InstanceEdit:9962055] Matthews, Lisa, 2025-07-30
nameFGFR1 R576W
referenceEntity[ReferenceGeneProduct:402793] UniProt:P11362 FGFR1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2297837] R-HSA-2011844.2
startCoordinate22
(hasCandidate)[CandidateSet:2012030] FGFR1 mutants with enhanced kinase activity [plasma membrane] [Homo sapiens]
(hasComponent)[Complex:2023419] FGFR1 R576W mutant dimer [plasma membrane] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9889933] Update Tracker - [EntityWithAccessionedSequence:2011844] FGFR1 R576W [plasma membrane] - v52:[modifyName]
[_UpdateTracker:9965132] Update Tracker - [EntityWithAccessionedSequence:2011844] FGFR1 R576W [plasma membrane] - v94:[add_removeDisease]
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No pathways have been reviewed or authored by FGFR1 R576W [plasma membrane] (2011844)