Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person The mitochondrial carnitine system catalyzes the transport o...
| Class:Id | Summation:201064 |
|---|---|
| _displayName | The mitochondrial carnitine system catalyzes the transport o... |
| _timestamp | 2024-05-29 20:01:56 |
| created | [InstanceEdit:201063] Gopinathrao, G, 2007-07-29 21:03:03 |
| modified | [InstanceEdit:9911357] D'Eustachio, Peter, 2024-05-29 |
| text | The mitochondrial carnitine system catalyzes the transport of long-chain fatty acids into the mitochondrial matrix where they undergo beta oxidation. This transport system consists of the malonyl-CoA sensitive carnitine palmitoyltransferase I (CPT-I) localized in the mitochondrial outer membrane, the carnitine:acylcarnitine translocase, an integral inner membrane protein, and carnitine palmitoyltransferase II localized on the matrix side of the inner membrane. (Kerner & Hoppel, 2000; Ramsay et al. 2001). Additional reactions annotated here enable the uptake of carnitine and the regulation of fatty acid biosynthesis at the level of ACACA and ACACB to minimize simultaeous mitochondrial catabolism and cytosolic biosynthesis of long-chain fatty acids. |
| (summation) | [Pathway:200425] Carnitine shuttle [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The mitochondrial carnitine system catalyzes the transport o... (201064)
