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Details on Person DOCK2:ELMO1:RAC1:Nef Complex [cytosol]

Class:Id	Complex:200937
_displayName	DOCK2:ELMO1:RAC1:Nef Complex [cytosol]
_timestamp	2014-05-21 09:11:10
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:200953] Gillespie, ME, 2007-07-26 04:51:49
hasComponent	[EntityWithAccessionedSequence:200938] DOCK2 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:200932] ELMO1 [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:167605] myristoylated nef [cytosol] [Human immunodeficiency virus 1] [EntityWithAccessionedSequence:442615] RAC1 [cytosol] [Homo sapiens]
modified	[InstanceEdit:2167930] D'Eustachio, P, 2012-03-23 [InstanceEdit:2169052] D'Eustachio, P, 2012-03-27 [InstanceEdit:3076315] Gillespie, ME, 2013-02-06 [InstanceEdit:5545433] Garapati, P V, 2014-05-21 [InstanceEdit:8959586] Weiser, JD
name	DOCK2:ELMO1:RAC1:Nef Complex
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:367952] R-HSA-200937.2
(output)	[Reaction:200952] Nef binds a ternary complex comprising DOCK2 guanine nucleotide exchange factor for small Rho-family GTPase Rac, its cofactor ELMO1, and Rac, and activates Rac through this interaction [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9867281] Update Tracker - [Complex:200937] DOCK2:ELMO1:RAC1:Nef Complex [cytosol] - v25:[updateContainedComponent] [_UpdateTracker:9872367] Update Tracker - [Complex:200937] DOCK2:ELMO1:RAC1:Nef Complex [cytosol] - v41:[updateContainedComponent] [_UpdateTracker:9878834] Update Tracker - [Complex:200937] DOCK2:ELMO1:RAC1:Nef Complex [cytosol] - v44:[add_removeHasComponent] [_UpdateTracker:9889685] Update Tracker - [Complex:200937] DOCK2:ELMO1:RAC1:Nef Complex [cytosol] - v49:[add_removeHasComponent] [_UpdateTracker:9896013] Update Tracker - [Complex:200937] DOCK2:ELMO1:RAC1:Nef Complex [cytosol] - v60:[removeSpecies]
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No pathways have been reviewed or authored by DOCK2:ELMO1:RAC1:Nef Complex [cytosol] (200937)