Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person FYN [cytosol]

Class:IdEntityWithAccessionedSequence:200917
_displayNameFYN [cytosol]
_timestamp2017-08-09 12:20:53
compartment[Compartment:70101] cytosol
created[InstanceEdit:200910] Gillespie, ME, 2007-07-25 21:18:02
endCoordinate537
modified[InstanceEdit:912661] Jupe, S, 2010-07-12
[InstanceEdit:1810385] Orlic-Milacic, M, 2011-10-24
[InstanceEdit:3632907] Wu, G, 2013-05-28
[InstanceEdit:4084621] Orlic-Milacic, M, 2013-07-30
[InstanceEdit:9015192] Duenas, Corina, 2017-08-09
nameFYN
Fyn
referenceEntity[ReferenceGeneProduct:55160] UniProt:P06241 FYN [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:365843] R-HSA-200917.2
startCoordinate2
(activeUnit)[CatalystActivity:399949] protein tyrosine kinase activity of Sema3A:Nrp-1:PlexinA:Fyn [plasma membrane]
[CatalystActivity:418882] protein tyrosine kinase activity of NTN1:DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane]
[CatalystActivity:912642] protein tyrosine kinase activity of FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol]
[CatalystActivity:5218846] protein tyrosine kinase activity of VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane]
[CatalystActivity:9038322] protein tyrosine kinase activity of Fyn:NCAM1:RPTP-alpha [plasma membrane]
(hasComponent)[Complex:200911] Fyn:Nef Complex [cytosol] [Homo sapiens]
[Complex:205256] Sky : Fyn complex [plasma membrane] [Homo sapiens]
[Complex:210253] GP6:Fyn complex [plasma membrane] [Homo sapiens]
[Complex:374555] p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane] [Homo sapiens]
[Complex:374603] p-Y605,Y606-KIRREL:FYN [plasma membrane] [Homo sapiens]
[Complex:391844] NCAM complexed with Fyn [plasma membrane] [Homo sapiens]
[Complex:399838] Fyn:pCdk5:p35 [plasma membrane] [Homo sapiens]
[Complex:399841] NRP1:Plexin-A1-4:FYN [plasma membrane] [Homo sapiens]
[Complex:399844] Plexin-A1-4:FYN [plasma membrane] [Homo sapiens]
[Complex:399847] Plexin-A1-4:FYN [plasma membrane] [Homo sapiens]
List all 23 refering instances
(hasMember)[DefinedSet:211064] Src family tyrosine kinases (SFKs) [cytosol] [Homo sapiens]
[DefinedSet:391344] SRC-1,FYN,YES1 [cytosol] [Homo sapiens]
[DefinedSet:418805] SRC,FYN [cytosol] [Homo sapiens]
[CandidateSet:912625] FYN-like kinases [cytosol] [Homo sapiens]
[DefinedSet:912670] FYN, HCK, LYN [cytosol] [Homo sapiens]
[DefinedSet:1861597] Src family kinases (SFKs) [cytosol] [Homo sapiens]
[DefinedSet:2395419] FYN,LCK [cytosol] [Homo sapiens]
[DefinedSet:3928486] SRC,FYN,YES,LYN [cytosol] [Homo sapiens]
[CandidateSet:5607667] Src family tyrosine kinases (SFKs) [cytosol] [Homo sapiens]
[DefinedSet:5621132] FYN, LYN [cytosol] [Homo sapiens]
List all 11 refering instances
(input)[Reaction:200908] Nef Binds and activates the Src-family tyrosine kinase Fyn [Homo sapiens]
[Reaction:205250] Interaction of Sky and Fyn [Homo sapiens]
[Reaction:210302] Interaction of GP6 and Fyn [Homo sapiens]
[Reaction:432295] GPVI binds Fyn and Lyn [Homo sapiens]
[Reaction:5218824] p-6Y-VEGFR2 binds FYN [Homo sapiens]
[Reaction:6785288] CSK phosphorylates FYN [Homo sapiens]
[Reaction:8954307] FYN binds KIRREL [Homo sapiens]
[Reaction:8981534] Nephrin dimer:KIRREL binds FYN [Homo sapiens]
[BlackBoxEvent:8983012] FYN and LCK bind IL7R [Homo sapiens]
[Reaction:9605259] Active FLT3 binds FYN [Homo sapiens]
List all 11 refering instances
(output)[Reaction:8955889] Dissociation of KIRREL:FYN [Homo sapiens]
(physicalEntity)[CatalystActivity:9038308] protein tyrosine kinase activity of FYN [cytosol]
(updatedInstance)[_UpdateTracker:9869759] Update Tracker - [EntityWithAccessionedSequence:200917] FYN [cytosol] - v34:[addName]
[_UpdateTracker:9870915] Update Tracker - [EntityWithAccessionedSequence:200917] FYN [cytosol] - v39:[modifyEndCoordinate, modifyStartCoordinate]
[_UpdateTracker:9886287] Update Tracker - [EntityWithAccessionedSequence:200917] FYN [cytosol] - v45:[addName]
[_UpdateTracker:9888318] Update Tracker - [EntityWithAccessionedSequence:200917] FYN [cytosol] - v46:[removeName]
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No pathways have been reviewed or authored by FYN [cytosol] (200917)