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Details on Person FYN [cytosol]
Class:Id EntityWithAccessionedSequence:200917
_displayName FYN [cytosol]
_timestamp 2017-08-09 12:20:53
compartment [Compartment:70101] cytosol
created [InstanceEdit:200910] Gillespie, ME, 2007-07-25 21:18:02
endCoordinate 537
modified [InstanceEdit:912661] Jupe, S, 2010-07-12 [InstanceEdit:1810385] Orlic-Milacic, M, 2011-10-24 [InstanceEdit:3632907] Wu, G, 2013-05-28 [InstanceEdit:4084621] Orlic-Milacic, M, 2013-07-30 [InstanceEdit:9015192] Duenas, Corina, 2017-08-09
name FYN Fyn
referenceEntity [ReferenceGeneProduct:55160] UniProt:P06241 FYN [Homo sapiens]
species [Species:48887] Homo sapiens
stableIdentifier [StableIdentifier:365843] R-HSA-200917.2
startCoordinate 2
(activeUnit) [CatalystActivity:399949] protein tyrosine kinase activity of Sema3A:Nrp-1:PlexinA:Fyn [plasma membrane] [CatalystActivity:418882] protein tyrosine kinase activity of NTN1:DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] [CatalystActivity:912642] protein tyrosine kinase activity of FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] [CatalystActivity:5218846] protein tyrosine kinase activity of VEGFA dimer:p-6Y-VEGFR2 dimer:NCK1,NCK2:FYN [plasma membrane] [CatalystActivity:9038322] protein tyrosine kinase activity of Fyn:NCAM1:RPTP-alpha [plasma membrane]
(hasComponent) [Complex:200911] Fyn:Nef Complex [cytosol] [Homo sapiens] [Complex:205256] Sky : Fyn complex [plasma membrane] [Homo sapiens] [Complex:210253] GP6:Fyn complex [plasma membrane] [Homo sapiens] [Complex:374555] p-Y1158,Y1176,Y1193,Y1217-NPHS1:KIRREL:FYN [plasma membrane] [Homo sapiens] [Complex:374603] p-Y605,Y606-KIRREL:FYN [plasma membrane] [Homo sapiens] [Complex:391844] NCAM complexed with Fyn [plasma membrane] [Homo sapiens] [Complex:399838] Fyn:pCdk5:p35 [plasma membrane] [Homo sapiens] [Complex:399841] NRP1:Plexin-A1-4:FYN [plasma membrane] [Homo sapiens] [Complex:399844] Plexin-A1-4:FYN [plasma membrane] [Homo sapiens] [Complex:399847] Plexin-A1-4:FYN [plasma membrane] [Homo sapiens]
(hasMember) [DefinedSet:211064] Src family tyrosine kinases (SFKs) [cytosol] [Homo sapiens] [DefinedSet:391344] SRC-1,FYN,YES1 [cytosol] [Homo sapiens] [DefinedSet:418805] SRC,FYN [cytosol] [Homo sapiens] [CandidateSet:912625] FYN-like kinases [cytosol] [Homo sapiens] [DefinedSet:912670] FYN, HCK, LYN [cytosol] [Homo sapiens] [DefinedSet:1861597] Src family kinases (SFKs) [cytosol] [Homo sapiens] [DefinedSet:2395419] FYN,LCK [cytosol] [Homo sapiens] [DefinedSet:3928486] SRC,FYN,YES,LYN [cytosol] [Homo sapiens] [CandidateSet:5607667] Src family tyrosine kinases (SFKs) [cytosol] [Homo sapiens] [DefinedSet:5621132] FYN, LYN [cytosol] [Homo sapiens]
(input) [Reaction:200908] Nef Binds and activates the Src-family tyrosine kinase Fyn [Homo sapiens] [Reaction:205250] Interaction of Sky and Fyn [Homo sapiens] [Reaction:210302] Interaction of GP6 and Fyn [Homo sapiens] [Reaction:432295] GPVI binds Fyn and Lyn [Homo sapiens] [Reaction:5218824] p-6Y-VEGFR2 binds FYN [Homo sapiens] [Reaction:6785288] CSK phosphorylates FYN [Homo sapiens] [Reaction:8954307] FYN binds KIRREL [Homo sapiens] [Reaction:8981534] Nephrin dimer:KIRREL binds FYN [Homo sapiens] [BlackBoxEvent:8983012] FYN and LCK bind IL7R [Homo sapiens] [Reaction:9605259] Active FLT3 binds FYN [Homo sapiens]
(output) [Reaction:8955889] Dissociation of KIRREL:FYN [Homo sapiens]
(physicalEntity) [CatalystActivity:9038308] protein tyrosine kinase activity of FYN [cytosol]
(updatedInstance) [_UpdateTracker:9869759] Update Tracker - [EntityWithAccessionedSequence:200917] FYN [cytosol] - v34:[addName] [_UpdateTracker:9870915] Update Tracker - [EntityWithAccessionedSequence:200917] FYN [cytosol] - v39:[modifyEndCoordinate, modifyStartCoordinate] [_UpdateTracker:9886287] Update Tracker - [EntityWithAccessionedSequence:200917] FYN [cytosol] - v45:[addName] [_UpdateTracker:9888318] Update Tracker - [EntityWithAccessionedSequence:200917] FYN [cytosol] - v46:[removeName]
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Pathways
No pathways have been reviewed or authored by FYN [cytosol] (200917)