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Details on Person EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes

Class:Id	LiteratureReference:2008120
_displayName	EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes
_timestamp	2011-11-21 20:37:38
author	[Person:2008126] Grandal, MV [Person:2008121] Zandi, R [Person:2008124] Pedersen, MW [Person:2008122] Willumsen, BM [Person:2008127] van Deurs, B [Person:2008125] Poulsen, HS
created	[InstanceEdit:2008123] Orlic-Milacic, Marija, 2011-11-21
journal	Carcinogenesis
pages	1408-17
pubMedIdentifier	17372273
title	EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes
volume	28
year	2007
(literatureReference)	[Reaction:1225947] Binding of SHC1 to p-6Y-EGFR mutants [Homo sapiens] [Reaction:1225949] Binding of CBL to ligand-responsive p-6Y-EGFR mutants [Homo sapiens] [Reaction:5637766] Binding of SHC1 to p-5Y-EGFRvIII [Homo sapiens] [Reaction:5637792] PLC-gamma 1 binds to p-EGFRvIII mutant [Homo sapiens] [FailedReaction:5637794] EGFRvIII does not bind CBL [Homo sapiens] [Reaction:5637800] Dissociation of phosphorylated PLC-gamma 1 from p-EGFRvIII mutant [Homo sapiens]
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No pathways have been reviewed or authored by EGFRvIII escapes down-regulation due to impaired internalization and sorting to lysosomes (2008120)