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Details on Person Cytosolic MTHFR dimer catalyzes the reaction of 5,10-methyle...

Class:IdSummation:200725
_displayNameCytosolic MTHFR dimer catalyzes the reaction of 5,10-methyle...
_timestamp2007-07-23 20:23:19
created[InstanceEdit:200727] D'Eustachio, P, 2007-07-23 20:23:04
textCytosolic MTHFR dimer catalyzes the reaction of 5,10-methyleneTHF polyglutamate, NADPH, and H+ to form 5-methylTHF polyglutamate and NADP+. The specificity and importance of this reaction in vivo have been established through the study of patients deficient in the enzyme (Goyette et al. 1995).
(summation)[Reaction:200676] MTHFR dimer reduces 5,10-methylene-THFPG to 5-methyl-THFPG [Homo sapiens]
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