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Details on Person Mitochondrial FPGS-1 transforms THF to THFPG

Class:IdReaction:200682
_displayNameMitochondrial FPGS-1 transforms THF to THFPG
_doReleaseTRUE
_timestamp2020-12-10 13:56:07
catalystActivity[CatalystActivity:200730] tetrahydrofolylpolyglutamate synthase activity of FPGS-1 [mitochondrial matrix]
compartment[Compartment:5460] mitochondrial matrix
created[InstanceEdit:200727] D'Eustachio, P, 2007-07-23 20:23:04
input[SimpleEntity:200671] THF [mitochondrial matrix]
[SimpleEntity:113593] ATP [mitochondrial matrix]
[SimpleEntity:113593] ATP [mitochondrial matrix]
[SimpleEntity:113593] ATP [mitochondrial matrix]
[SimpleEntity:113593] ATP [mitochondrial matrix]
[SimpleEntity:113593] ATP [mitochondrial matrix]
[SimpleEntity:113593] ATP [mitochondrial matrix]
[SimpleEntity:113552] L-Glu [mitochondrial matrix]
[SimpleEntity:113552] L-Glu [mitochondrial matrix]
[SimpleEntity:113552] L-Glu [mitochondrial matrix]
[SimpleEntity:113552] L-Glu [mitochondrial matrix]
[SimpleEntity:113552] L-Glu [mitochondrial matrix]
[SimpleEntity:113552] L-Glu [mitochondrial matrix]
literatureReference[LiteratureReference:197962] Expression cloning of a human cDNA encoding folylpoly(gamma-glutamate) synthetase and determination of its primary structure
[LiteratureReference:200690] Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene
modified[InstanceEdit:200987] Gopinathrao, G, 2007-07-27 15:28:23
[InstanceEdit:201332] Gopinathrao, G, 2007-08-06 14:46:29
[InstanceEdit:732460] D'Eustachio, P, 2010-05-12
[InstanceEdit:9709130] Jassal, Bijay, 2020-12-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameMitochondrial FPGS-1 transforms THF to THFPG
Conversion of mitochondrial THF to THF-polyglutamate
output[SimpleEntity:200679] THFPG [mitochondrial matrix]
[SimpleEntity:113581] ADP [mitochondrial matrix]
[SimpleEntity:113581] ADP [mitochondrial matrix]
[SimpleEntity:113581] ADP [mitochondrial matrix]
[SimpleEntity:113581] ADP [mitochondrial matrix]
[SimpleEntity:113581] ADP [mitochondrial matrix]
[SimpleEntity:113581] ADP [mitochondrial matrix]
[SimpleEntity:113548] Pi [mitochondrial matrix]
[SimpleEntity:113548] Pi [mitochondrial matrix]
[SimpleEntity:113548] Pi [mitochondrial matrix]
[SimpleEntity:113548] Pi [mitochondrial matrix]
[SimpleEntity:113548] Pi [mitochondrial matrix]
[SimpleEntity:113548] Pi [mitochondrial matrix]
precedingEvent
releaseDate2007-08-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:361281] R-HSA-200682.3
summation[Summation:200637] Mitochondrial folylpolyglutamate synthase catalyzes the reac...
(hasEvent)[Pathway:196757] Metabolism of folate and pterines [Homo sapiens]
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