Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person SLC19A1 transports 5-methyl-THF from extracellular region to cytosol

Class:IdReaction:200652
_displayNameSLC19A1 transports 5-methyl-THF from extracellular region to cytosol
_doReleaseTRUE
_timestamp2020-12-10 13:56:22
catalystActivity[CatalystActivity:200705] folic acid transmembrane transporter activity of SLC19A1 [plasma membrane]
compartment[Compartment:876] plasma membrane
created[InstanceEdit:200727] D'Eustachio, P, 2007-07-23 20:23:04
input[SimpleEntity:200709] 5-methyl-THF [extracellular region]
literatureReference[LiteratureReference:200668] Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake
[LiteratureReference:200685] Topological and functional analysis of the human reduced folate carrier by hemagglutinin epitope insertion
modified[InstanceEdit:200987] Gopinathrao, G, 2007-07-27 15:28:23
[InstanceEdit:201332] Gopinathrao, G, 2007-08-06 14:46:29
[InstanceEdit:732460] D'Eustachio, P, 2010-05-12
[InstanceEdit:9709130] Jassal, Bijay, 2020-12-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSLC19A1 transports 5-methyl-THF from extracellular region to cytosol
Extracellular 5-methyltetrahydrofolate import across the plasma membrane
output[SimpleEntity:200665] 5-methyl-THF [cytosol]
releaseDate2007-08-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358372] R-HSA-200652.3
summation[Summation:200712] SLC19A1 protein, associated with the plasma membrane, mediat...
(hasEvent)[Pathway:196757] Metabolism of folate and pterines [Homo sapiens]
(precedingEvent)[Reaction:200681] FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by SLC19A1 transports 5-methyl-THF from extracellular region to cytosol (200652)
Follow Reactome