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Details on Person C1-Tetrahydrofolate synthase from rabbit liver. Structural and kinetic properties of the enzyme and its two domains.

Class:IdLiteratureReference:200643
_displayNameC1-Tetrahydrofolate synthase from rabbit liver. Structural and kinetic properties of the enzyme and its two domains.
_timestamp2007-07-23 20:23:19
author[Person:200741] Villar, E
[Person:200648] Schuster, B
[Person:200695] Peterson, D
[Person:200742] Schirch, V
created[InstanceEdit:200727] D'Eustachio, P, 2007-07-23 20:23:04
journalJ Biol Chem
pages2245-52
pubMedIdentifier3871768
titleC1-Tetrahydrofolate synthase from rabbit liver. Structural and kinetic properties of the enzyme and its two domains.
volume260
year1985
(literatureReference)[Reaction:200644] 5,10-methyleneTHF polyglutamate + NADP+ <=> 5,10-methenylTHF polyglutamate + NADPH + H+ [Homo sapiens]
[Reaction:200661] MTHFD1 dimer transforms 10-formyl-THFPG to 5,10-methenyl-THFPG [Homo sapiens]
[Reaction:200711] MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG [Homo sapiens]
[Reaction:200718] MTHFD1 dimer dehydrogenates 5,10-methenyl-THFPG to 5,10-methylene-THFPG [Homo sapiens]
[Reaction:200740] 5,10-methenylTHF polyglutamate + H2O <=> 10-formylTHF polyglutamate [Homo sapiens]
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