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Details on Person CPT2 converts acylcarnitine to acyl-CoA

Class:IdReaction:200410
_displayNameCPT2 converts acylcarnitine to acyl-CoA
_doReleaseTRUE
_timestamp2025-11-07 17:19:12
authored[InstanceEdit:201063] Gopinathrao, G, 2007-07-29 21:03:03
catalystActivity[CatalystActivity:201039] carnitine O-acyltransferase activity of CPT2 [mitochondrial inner membrane]
catalystActivityReference[CatalystActivityReference:9643316] carnitine O-acyltransferase activity of CPT2 [mitochondrial inner membrane] Carnitine palmitoyltransferase II deficiency: structure of the gene and characterization of two novel disease-causing mutations
compartment[Compartment:70616] mitochondrial inner membrane
[Compartment:5460] mitochondrial matrix
created[InstanceEdit:200415] Gopinathrao, G, 2007-07-18 19:50:24
crossReference[DatabaseIdentifier:9911358] RHEA:12663
[DatabaseIdentifier:9971086] RHEA:40281
input[SimpleEntity:29374] CoA-SH [mitochondrial matrix]
[DefinedSet:9971105] C8-C18 Acyl-CAR [mitochondrial matrix]
internalReviewed[InstanceEdit:9971584] D'Eustachio, Peter, 2025-11-07
literatureReference[LiteratureReference:201349] Carnitine palmitoyltransferase II deficiency: structure of the gene and characterization of two novel disease-causing mutations
[LiteratureReference:9911356] Carnitine palmitoyltransferase 2: New insights on the substrate specificity and implications for acylcarnitine profiling
modified[InstanceEdit:201001] Gopinathrao, G, 2007-07-29 16:52:53
[InstanceEdit:201062] Gopinathrao, G, 2007-07-29 16:59:33
[InstanceEdit:201070] Gopinathrao, G, 2007-07-30 14:54:02
[InstanceEdit:201092] Gopinathrao, G, 2007-07-31 11:22:43
[InstanceEdit:201317] Gopinathrao, G, 2007-08-03 18:51:55
[InstanceEdit:201348] Gopinathrao, G, 2007-08-06 19:51:09
[InstanceEdit:549212] D'Eustachio, P, 2010-03-18
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9643047] Wu, G, 2019-04-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9911357] D'Eustachio, Peter, 2024-05-29
[InstanceEdit:9971108] Stephan, Ralf, 2025-11-04
[InstanceEdit:9971587] D'Eustachio, Peter, 2025-11-07
[InstanceEdit:9971589] D'Eustachio, Peter, 2025-11-07
nameCPT2 converts acylcarnitine to acyl-CoA
palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine
output[SimpleEntity:201023] CAR [mitochondrial matrix]
[DefinedSet:9971103] C8-C18 Acyl-CoA [mitochondrial matrix]
precedingEvent
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2005-09-26
reviewed[InstanceEdit:201322] D'Eustachio, P, 2007-07-31 18:50:15
[InstanceEdit:9971588] D'Eustachio, Peter, 2025-11-07
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359397] R-HSA-200410.6
structureModified[InstanceEdit:9971108] Stephan, Ralf, 2025-11-04
summation[Summation:201075] CPT2, associated with the inner mitochondrial membrane, cata...
(hasEvent)[Pathway:200425] Carnitine shuttle [Homo sapiens]
(precedingEvent)[Pathway:77305] Beta oxidation of palmitoyl-CoA to myristoyl-CoA [Homo sapiens]
(updatedInstance)[_UpdateTracker:9790508] Update Tracker - [Reaction:200410] palmitoylcarnitine + CoASH => palmitoyl-CoA + carnitine - v33:[modifyText]
[_UpdateTracker:9919457] Update Tracker - [Reaction:200410] CPT2 converts palmitoyl carnitine to palmitoyl-CoA - v90:[modifyText, removeLiteratureReference]
[_UpdateTracker:9971848] Update Tracker - [Reaction:200410] CPT2 converts acylcarnitine to acyl-CoA - v95:[add_removeInput, add_removeOutput, modifyText]
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