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Details on Person UniProt:Q96NU7 AMDHD1

Class:IdReferenceGeneProduct:200053
_chainChangeLogchain:1-426 added on Fri February 6 2015
_displayNameUniProt:Q96NU7 AMDHD1
_timestamp2024-11-03 19:56:41
chainchain:1-426
checksumAD747F82BD00ACD3
commentCATALYTIC ACTIVITY 4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamateCOFACTOR Binds 1 zinc or iron ion per subunit.PATHWAY Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3.INTERACTION Belongs to the metallo-dependent hydrolases superfamily. HutI family.SEQUENCE CAUTION Extended N-terminus.
created[InstanceEdit:200032] D'Eustachio, P, 2007-07-13 20:48:01
descriptionrecommendedName: Probable imidazolonepropionase ecNumber: 3.5.2.7 alternativeName: Amidohydrolase domain-containing protein 1
geneNameAMDHD1
HMFT1272
identifierQ96NU7
isSequenceChangedFALSE
keywordHistidine metabolism
Hydrolase
Iron
Metal-binding
Proteomics identification
Reference proteome
Zinc
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
[InstanceEdit:9926675] Weiser, Joel, 2024-11-03
nameAMDHD1
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:9001811] ENSEMBL:ENSG00000139344 AMDHD1 [Homo sapiens]
secondaryIdentifierHUTI_HUMAN
A8K463
Q68CI8
sequenceLength426
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:70904] AMDHD1 [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:Q96NU7 AMDHD1 (200053)