Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person p-6Y-EGFR N771_H773dup [plasma membrane]

Class:IdEntityWithAccessionedSequence:1996342
_displayNamep-6Y-EGFR N771_H773dup [plasma membrane]
_timestamp2023-03-21 14:56:19
compartment[Compartment:876] plasma membrane
created[InstanceEdit:1996337] Orlic-Milacic, Marija, 2011-11-19
crossReference[DatabaseIdentifier:1996302] COSMIC:COSV51772596
disease[Disease:1500689] cancer
[Disease:1500699] lung cancer
[Disease:1247848] non-small cell lung carcinoma
endCoordinate1210
hasModifiedResidue[FragmentInsertionModification:1996331] Insertion of residues 771 to 773 at 774 from UniProt:P00533 EGFR
[ModifiedResidue:182927] O4'-phospho-L-tyrosine at 1069
[ModifiedResidue:179797] O4'-phospho-L-tyrosine at 1092
[ModifiedResidue:179834] O4'-phospho-L-tyrosine at 1110
[ModifiedResidue:179844] O4'-phospho-L-tyrosine at 1172
[ModifiedResidue:179872] O4'-phospho-L-tyrosine at 1197
[ModifiedResidue:180321] O4'-phospho-L-tyrosine at 1016
modified[InstanceEdit:3662293] Orlic-Milacic, M, 2013-06-06
[InstanceEdit:9831495] Orlic-Milacic, Marija, 2023-03-21
namep-6Y-EGFR N771_H773dup
Phosphorylated Epidermal Growth Factor Receptor N771_H773dup
p-6Y-EGFR Asn771_His773dup
referenceEntity[ReferenceGeneProduct:54208] UniProt:P00533 EGFR [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2016838] R-HSA-1996342.2
startCoordinate25
(hasCandidate)[CandidateSet:1182982] Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs [plasma membrane] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9887594] Update Tracker - [EntityWithAccessionedSequence:1996342] p-6Y-EGFR N771_H773dup [plasma membrane] - v46:[modifyName]
[_UpdateTracker:9905773] Update Tracker - [EntityWithAccessionedSequence:1996342] p-6Y-EGFR N771_H773dup [plasma membrane] - v85:[modifyName]
[Change default viewing format]
No pathways have been reviewed or authored by p-6Y-EGFR N771_H773dup [plasma membrane] (1996342)