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Details on Person HLA-C Cw3 (group 1) [plasma membrane]

Class:Id	Complex:199562
_displayName	HLA-C Cw3 (group 1) [plasma membrane]
_timestamp	2023-02-06 14:35:36
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:199559] de Bono, B, 2007-07-11 12:39:45
hasComponent	[EntityWithAccessionedSequence:167743] B2M(21-119) [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:199595] HLA class I histocompatibility antigen, Cw-7 alpha chain precursor [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:199529] The KIR gene family: life in the fast lane of evolution [LiteratureReference:199545] Amino acid substitutions can influence the natural killer (NK)-mediated recognition of HLA-C molecules. Role of serine-77 and lysine-80 in the target cell protection from lysis mediated by "group 2" or "group 1" NK clones.
modified	[InstanceEdit:2245300] Garapati, P V, 2012-05-11 [InstanceEdit:9827436] D'Eustachio, Peter, 2023-01-31 [InstanceEdit:9827795] D'Eustachio, Peter, 2023-02-06
name	HLA-C Cw3 (group 1)
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:371904] R-HSA-199562.2
(hasComponent)	[Complex:199560] HLA-C group 2 interacting with KIR2DL1 [plasma membrane] [Homo sapiens] [Complex:199588] HLA-C group 1 interacting with KIR2DS2 [plasma membrane] [Homo sapiens] [Complex:2272718] KIR2DS2:HLA-C1 (Cw3) [plasma membrane] [Homo sapiens]
(hasMember)	[CandidateSet:199614] MHC Class I molecules interacting with CD160 [plasma membrane] [Homo sapiens] [DefinedSet:2272698] HLA-C Cw3/HLA-C Cw4 [plasma membrane] [Homo sapiens]
(input)	[Reaction:199558] KIR2DL1 interacting with HLA-C group 2 (Cw3) [Homo sapiens] [Reaction:199583] KIR2DS2 interacting with HLA-C group 1 (Cw3) [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9872482] Update Tracker - [Complex:199562] HLA-C Cw3 (group 1) [plasma membrane] - v41:[modifyName] [_UpdateTracker:9904961] Update Tracker - [Complex:199562] HLA-C Cw3 (group 1) [plasma membrane] - v84:[add_removeHasComponent]
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No pathways have been reviewed or authored by HLA-C Cw3 (group 1) [plasma membrane] (199562)