Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person p-S939,T1462-TSC2 [cytosol]

Class:IdEntityWithAccessionedSequence:199484
_displayNamep-S939,T1462-TSC2 [cytosol]
_timestamp2013-05-09 15:03:37
compartment[Compartment:70101] cytosol
created[InstanceEdit:199481] Jassal, B, 2007-07-11 09:33:46
endCoordinate1807
hasModifiedResidue[ModifiedResidue:199480] O-phospho-L-serine at 939
[ModifiedResidue:199482] O-phospho-L-threonine at 1462
modified[InstanceEdit:199866] Jassal, B, 2007-07-12 14:41:47
[InstanceEdit:1531240] Orlic-Milacic, Marija, 2011-08-25
[InstanceEdit:2400004] Orlic-Milacic, M, 2012-07-13
[InstanceEdit:2980545] Jassal, B, 2013-01-11
[InstanceEdit:3322333] Wu, G, 2013-05-03
[InstanceEdit:3322334] Wu, G, 2013-05-03
[InstanceEdit:3325515] Orlic-Milacic, M, 2013-05-09
namep-S939,T1462-TSC2
Phospho-TSC2
referenceEntity[ReferenceGeneProduct:404219] UniProt:P49815 TSC2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:367580] R-HSA-199484.1
startCoordinate1
(hasComponent)[Complex:5632727] p-S939,T1462-TSC2:14-3-3 dimer [cytosol] [Homo sapiens]
(input)[Reaction:5632732] p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 [Homo sapiens]
(output)[Reaction:198609] AKT phosphorylates TSC2, inhibiting it [Homo sapiens]
[Reaction:2399982] AKT1 E17K mutant phosphorylates TSC2, inhibiting it [Homo sapiens]
(updatedInstance)[_UpdateTracker:9870243] Update Tracker - [EntityWithAccessionedSequence:199484] p-S939,T1462-TSC2 [cytosol] - v38:[addName]
[_UpdateTracker:9873176] Update Tracker - [EntityWithAccessionedSequence:199484] p-S939,T1462-TSC2 [cytosol] - v42:[addEndCoordinate, addStartCoordinate]
[_UpdateTracker:9876130] Update Tracker - [EntityWithAccessionedSequence:199484] p-S939,T1462-TSC2 [cytosol] - v44:[add_removeReferenceEntity, modifyName]
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No pathways have been reviewed or authored by p-S939,T1462-TSC2 [cytosol] (199484)