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Details on Person Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Class:IdLiteratureReference:199373
_displayNamePhosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
_timestamp2007-07-10 08:11:05
author[Person:199349] Sarbassov, DD
[Person:199345] Guertin, DA
[Person:165693] Ali, SM
[Person:165691] Sabatini, DM
created[InstanceEdit:199370] Jassal, B, 2007-07-10 08:08:36
journalScience
pages1098-101
pubMedIdentifier15718470
titlePhosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
volume307
year2005
(literatureReference)[Summation:198363] Once AKT is localized at the plasma membrane, it is phosphor...
[Summation:202051] Under conditions of growth and mitogen stimulation S473 phos...
[Summation:2326766] Once phosphorylated on serine residue S473, AKT bound to PIP...
[Summation:9863604] Suppression of PKN2 eliminates the phosphorylation of AKT1 o...
[Reaction:198640] mTORC2 phosphorylates AKT at S473 [Homo sapiens]
[Reaction:201527] PDK2 phosphorylates AKT at T308 and S473 [Homo sapiens]
[Reaction:377209] TOR phosphorylates AKT1 [Drosophila melanogaster]
[Reaction:377444] Activated TOR phosphorylates AKT1 [Drosophila melanogaster]
[Reaction:2317314] AKT binds PDPK1 [Homo sapiens]
[Reaction:9860800] mTORC2 phosphorylates AKT1 on serine-473 [Homo sapiens]
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