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Details on Person HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

Class:IdLiteratureReference:199351
_displayNameHER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
_timestamp2007-07-10 08:10:58
author[Person:199366] Zhou, BP
[Person:195538] Liao, Y
[Person:199334] Xia, W
[Person:199350] Zou, Y
[Person:199360] Spohn, B
[Person:199335] Hung, MC
created[InstanceEdit:199370] Jassal, B, 2007-07-10 08:08:36
journalNat Cell Biol
pages973-82
pubMedIdentifier11715018
titleHER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
volume3
year2001
(literatureReference)[Reaction:198599] AKT phosphorylates MDM2 [Homo sapiens]
[Reaction:2399981] AKT1 E17K mutant phosphorylates MDM2 [Homo sapiens]
[Pathway:6804757] Regulation of TP53 Degradation [Homo sapiens]
[Summation:198607] AKT phosphorylates MDM2 on two serine residues, at positions...
[Summation:2399983] AKT1 E17K gain-of-function mutant is expected to phosphoryla...
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