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Details on Person FOXO1 [nucleoplasm]

Class:IdEntityWithAccessionedSequence:199300
_displayNameFOXO1 [nucleoplasm]
_timestamp2012-07-13 17:13:42
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:199263] Jassal, B, 2007-07-10 07:58:55
endCoordinate655
modified[InstanceEdit:2400004] Orlic-Milacic, M, 2012-07-13
nameFOXO1
Forkhead box protein O1A
FOXO1_HUMAN
FOXO1A
referenceEntity[ReferenceGeneProduct:199304] UniProt:Q12778 FOXO1 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:366657] R-HSA-199300.1
startCoordinate1
(activeUnit)[PositiveGeneExpressionRegulation:9622989] Positive gene expression regulation by 'FOXO1:NPY gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:9623040] Positive gene expression regulation by 'FOXO1:AGRP gene [nucleoplasm]'
[NegativeGeneExpressionRegulation:9623083] Negative gene expression regulation by 'FOXO1:POMC gene [nucleoplasm]'
[NegativeGeneExpressionRegulation:9625364] Negative gene expression regulation by 'FOXO1:SREBF1 gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:9625536] Positive gene expression regulation by 'FOXO1:p-2S-Smad2/3:Smad4:Mstn gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:9625537] Positive gene expression regulation by 'FOXO1:p-2S-SMAD2/3:SMAD4:MSTN gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:9625742] Positive gene expression regulation by 'FOXO1:NR3C1:(ALDO,11DCORST,CORST,CORT):TRIM63 gene [nucleoplasm]'
[PositiveGeneExpressionRegulation:9625832] Positive gene expression regulation by 'FOXO1:RETN gene [nucleoplasm]'
(hasCandidate)[CandidateSet:9617860] FOXO3,FOXO4,(FOXO1) [nucleoplasm] [Homo sapiens]
[CandidateSet:9618003] FOXO3,(FOXO1,FOXO4) [nucleoplasm] [Homo sapiens]
[CandidateSet:9622696] FOXO3,(FOXO1) [nucleoplasm] [Homo sapiens]
[CandidateSet:9622805] FOXO3,FOXO6,(FOXO1) [nucleoplasm] [Homo sapiens]
(hasComponent)[Complex:9622979] FOXO1:NPY gene [nucleoplasm] [Homo sapiens]
[Complex:9623048] FOXO1:AGRP gene [nucleoplasm] [Homo sapiens]
[Complex:9623080] FOXO1:POMC gene [nucleoplasm] [Homo sapiens]
[Complex:9623234] FOXO1:PPARGC1A [nucleoplasm] [Homo sapiens]
[Complex:9624652] FOXO1:Fbxo32 gene [nucleoplasm] [Homo sapiens]
[Complex:9625141] FOXO1:SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] [Homo sapiens]
[Complex:9625360] FOXO1:SREBF1 gene [nucleoplasm] [Homo sapiens]
[Complex:9625499] FOXO1:p-2S-SMAD2/3:SMAD4:MSTN gene [nucleoplasm] [Homo sapiens]
[Complex:9625505] FOXO1:p-2S-Smad2/3:Smad4:Mstn gene [nucleoplasm] [Homo sapiens]
[Complex:9625735] FOXO1:NR3C1:(ALDO,11DCORST,CORST,CORT):TRIM63 gene [nucleoplasm] [Homo sapiens]
List all 12 refering instances
(hasMember)[CandidateSet:199272] FOXO1,FOXO3,FOXO4,(FOXO6) [nucleoplasm] [Homo sapiens]
[DefinedSet:500385] Proteins Encoded by Genes Activated by OCT4:SOX2:NANOG [nucleoplasm] [Homo sapiens]
[DefinedSet:6790042] STAT3-upregulated nuclear proteins [nucleoplasm] [Homo sapiens]
[DefinedSet:9614686] FOXO1,FOXO3 [nucleoplasm] [Homo sapiens]
[DefinedSet:9617987] FOXO1,FOXO3,FOXO4 [nucleoplasm] [Homo sapiens]
[CandidateSet:9620827] FOXO1,FOXO3,(FOXO4) [nucleoplasm] [Homo sapiens]
[DefinedSet:9623256] FOXO1,FOXO1:PPARGC1A,FOXO3,FOXO4,FOXO6 [nucleoplasm] [Homo sapiens]
[CandidateSet:9625445] FOXO1,(FOXO3) [nucleoplasm] [Homo sapiens]
(input)[Reaction:211164] AKT phosphorylates FOXO1A [Homo sapiens]
[Reaction:5692779] p-T182 MAPKAPK5 phosphorylates FOXO1 [Homo sapiens]
[Reaction:9622980] FOXO1 binds NPY gene promoter [Homo sapiens]
[Reaction:9623018] FOXO1 binds AGRP gene promoter [Homo sapiens]
[Reaction:9623059] FOXO1 binds POMC gene promoter [Homo sapiens]
[Reaction:9623240] FOXO1 binds PPARGC1A [Homo sapiens]
[Reaction:9624599] FOXO1 binds Fbxo32 gene promoter [Homo sapiens]
[Reaction:9625101] FOXO1 and SIN3A:HDAC complex bind GCK gene promoter [Homo sapiens]
[Reaction:9625324] FOXO1 binds SREBF1 gene promoter [Homo sapiens]
[Reaction:9625492] FOXO1 and p-2S-Smad2/3:Smad4 bind Mstn gene promoter [Homo sapiens]
List all 14 refering instances
(output)[BlackBoxEvent:480238] Expression of FOXO1A [Homo sapiens]
[BlackBoxEvent:9621423] FOXO1 mRNA translation is inhibited by microRNAs [Homo sapiens]
[Reaction:9626962] SIRT1 deacetylates FOXO1 [Homo sapiens]
(regulator)[NegativeGeneExpressionRegulation:211284] Negative gene expression regulation by 'FOXO1 [nucleoplasm]'
[PositiveRegulation:9617959] Positive regulation by 'FOXO1 [nucleoplasm]'
[NegativeRegulation:9625358] Negative regulation by 'FOXO1 [nucleoplasm]'
(updatedInstance)[_UpdateTracker:9873116] Update Tracker - [EntityWithAccessionedSequence:199300] FOXO1 [nucleoplasm] - v42:[addName]
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No pathways have been reviewed or authored by FOXO1 [nucleoplasm] (199300)