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Details on Person SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol

Class:IdReaction:199206
_displayNameSLC5A6 cotransports extracellular PanK and 2Na+ to cytosol
_doReleaseTRUE
_timestamp2023-06-12 22:16:01
authored[InstanceEdit:199189] D'Eustachio, P, 2007-07-09 22:03:12
catalystActivity[CatalystActivity:199212] sodium-dependent multivitamin transmembrane transporter activity of SLC5A6:PDZD11 [plasma membrane]
catalystActivityReference[CatalystActivityReference:9837298] sodium-dependent multivitamin transmembrane transporter activity of SLC5A6:PDZD11 [plasma membrane] Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter
compartment[Compartment:876] plasma membrane
created[InstanceEdit:199189] D'Eustachio, P, 2007-07-09 22:03:12
input[SimpleEntity:199192] PanK [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
[SimpleEntity:74113] Na+ [extracellular region]
literatureReference[LiteratureReference:5359001] Association of PDZ-containing protein PDZD11 with the human sodium-dependent multivitamin transporter
[LiteratureReference:9837288] Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate
[LiteratureReference:199217] Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter
[LiteratureReference:199231] Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization.
modified[InstanceEdit:199241] D'Eustachio, P, 2007-07-09 22:09:46
[InstanceEdit:200987] Gopinathrao, G, 2007-07-27 15:28:23
[InstanceEdit:732460] D'Eustachio, P, 2010-05-12
[InstanceEdit:3165246] Jassal, B, 2013-02-22
[InstanceEdit:5359003] Jassal, Bijay, 2014-04-07
[InstanceEdit:5362694] Jassal, Bijay, 2014-04-17
[InstanceEdit:8946993] Shorser, Solomon, 2016-11-07
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9837287] D'Eustachio, Peter, 2023-06-12
nameSLC5A6 cotransports extracellular PanK and 2Na+ to cytosol
(R)-pantothenate(out) + 2 Na(+)(out) = (R)-pantothenate(in) + 2 Na(+)(in)
output[SimpleEntity:196820] PanK [cytosol]
[SimpleEntity:83910] Na+ [cytosol]
[SimpleEntity:83910] Na+ [cytosol]
releaseDate2007-09-04
reviewStatus[ReviewStatus:9821382] five stars
revised[InstanceEdit:5359004] Jassal, Bijay, 2014-04-07
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:360926] R-HSA-199206.4
summation[Summation:199226] The plasma membrane-associated transport protein SLC5A6 (SMV...
(hasEvent)[Pathway:199220] Vitamin B5 (pantothenate) metabolism [Homo sapiens]
(precedingEvent)[Reaction:196857] PANK2 phosphorylates PanK [Homo sapiens]
[Reaction:199203] PANK1/3 phosphorylate PanK [Homo sapiens]
(updatedInstance)[_UpdateTracker:9786487] Update Tracker - [Reaction:199206] SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol - v49:[addLiteratureReference, modifyText]
[_UpdateTracker:9787821] Update Tracker - [Reaction:199206] SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol - v44:[modifyText]
[_UpdateTracker:9842329] Update Tracker - [Reaction:199206] SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol - v86:[addLiteratureReference, modifyText]
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