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Details on Person Expression of FATP1 (SLC27A1)

Class:Id	BlackBoxEvent:1989750
_displayName	Expression of FATP1 (SLC27A1)
_doRelease	TRUE
_timestamp	2025-07-21 16:37:45
authored	[InstanceEdit:1989769] May, B, 2011-11-08
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:1989763] May, B, 2011-11-13
edited	[InstanceEdit:1989769] May, B, 2011-11-08
goBiologicalProcess	[GO_BiologicalProcess:17788] positive regulation of transcription by RNA polymerase II
input	[EntityWithAccessionedSequence:5649954] SLC27A1 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:1989689] Peroxisome proliferator-activated receptor alpha (PPARalpha ) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes
modified	[InstanceEdit:5649962] May, Bruce, 2014-11-24 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9626992] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9961204] D'Eustachio, Peter, 2025-07-21
name	Expression of FATP1 (SLC27A1)
output	[EntityWithAccessionedSequence:400190] SLC27A1 [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:400143] Fatty acid ligands activate PPARA [Homo sapiens] [BlackBoxEvent:400183] PPARA:RXRA binds Corepressors of PPARA [Homo sapiens] [Reaction:2026996] FABP1 transports fatty acids into the nucleus [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:1989799] Positive gene expression regulation by 'PPARA:RXRA Coactivator complex [nucleoplasm]'
regulationReference	[RegulationReference:9642227] Positive gene expression regulation by 'PPARA:RXRA Coactivator complex [nucleoplasm]' Peroxisome proliferator-activated receptor alpha (PPARalpha ) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes
releaseDate	2011-12-06
reviewed	[InstanceEdit:425906] Kersten, S, 2009-06-08
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2016545] R-HSA-1989750.6
summation	[Summation:1989642] The FATP1 (SLC27A1) gene is transcribed to yield mRNA and th...
(hasEvent)	[Pathway:1989781] PPARA activates gene expression [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9784878] Update Tracker - [BlackBoxEvent:1989750] Expression of FATP1 (SLC27A1) - v52:[addInput]
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No pathways have been reviewed or authored by Expression of FATP1 (SLC27A1) (1989750)