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Details on Person The reduction of cytosolic semidehydroascorbate (SDA) to asc...

Class:IdSummation:198840
_displayNameThe reduction of cytosolic semidehydroascorbate (SDA) to asc...
_timestamp2019-03-25 14:26:40
created[InstanceEdit:198855] D'Eustachio, P, 2007-07-05 13:28:49
literatureReference[LiteratureReference:198875] Vitamin C: biosynthesis, recycling and degradation in mammals
modified[InstanceEdit:198876] D'Eustachio, P, 2007-07-05 13:41:18
[InstanceEdit:3165246] Jassal, B, 2013-02-22
[InstanceEdit:9640304] Jassal, Bijay, 2019-03-25
textThe reduction of cytosolic semidehydroascorbate (SDA) to ascorbate (AscH-) is catalyzed by cytochrome B5 (CYB5A) associated with the mitochondrial outer membrane. In the course of the reaction, the heme iron of the cytochrome is oxidized (Linster & Van Schaftingen 2007, Shirabe et al. 1995).
(summation)[Reaction:198845] CYB5A:heme reduces Asc.- to AscH- [Homo sapiens]
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