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Details on Person ERK1/2 activates ELK1

Class:Id	Reaction:198706
_displayName	ERK1/2 activates ELK1
_doRelease	TRUE
_timestamp	2018-10-19 19:27:38
catalystActivity	[CatalystActivity:198694] protein serine/threonine kinase activity of Phospho-ERK [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:198764] 2007-07-10 08:01:57
input	[EntityWithAccessionedSequence:198712] ETS-domain protein Elk-1 [nucleoplasm] [Mus musculus] [SimpleEntity:29358] ATP [nucleoplasm] [SimpleEntity:29358] ATP [nucleoplasm] [SimpleEntity:29358] ATP [nucleoplasm] [SimpleEntity:29358] ATP [nucleoplasm] [SimpleEntity:29358] ATP [nucleoplasm]
literatureReference	[LiteratureReference:199346] ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation [LiteratureReference:9625301] The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain [LiteratureReference:9625249] Estrogen receptor-mediated activation of the serum response element in MCF-7 cells through MAPK-dependent phosphorylation of Elk-1 [LiteratureReference:9625265] Journey to the surface of the cell: Fos regulation and the SRE
modified	[InstanceEdit:199255] Jassal, B, 2007-07-10 07:58:34 [InstanceEdit:199370] Jassal, B, 2007-07-10 08:08:36 [InstanceEdit:211298] Jassal, B, 2008-01-30 10:40:56 [InstanceEdit:211746] Jassal, B, 2008-02-08 11:38:28 [InstanceEdit:215417] Jassal, B, 2008-02-28 15:14:23 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9625458] Rothfels, Karen, 2018-10-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	ERK1/2 activates ELK1
output	[EntityWithAccessionedSequence:198757] Phospho-ETS-domain protein Elk-1 [nucleoplasm] [Mus musculus] [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm] [SimpleEntity:113582] ADP [nucleoplasm]
releaseDate	2006-01-23
reviewed	[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:361859] R-MMU-198706.4
summation	[Summation:198707] Following translocation to the nucleus, ERK1/2 directly phos...
(inferredFrom)	[Reaction:198731] ERK1/2 activates ELK1 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9778322] Update Tracker - [Reaction:198706] ERK1/2 activates ELK1 - v68:[modifyText] [_UpdateTracker:9778938] Update Tracker - [Reaction:198706] ERK1/2 activates ELK1 - v67:[addLiteratureReference, modifyText]
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No pathways have been reviewed or authored by ERK1/2 activates ELK1 (198706)