Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person ADRBK1 (also known as GRK2) is phosphorylated at serine 29 i...
| Class:Id | Summation:1986604 |
|---|---|
| _displayName | ADRBK1 (also known as GRK2) is phosphorylated at serine 29 i... |
| _timestamp | 2016-11-14 20:37:38 |
| created | [InstanceEdit:1986603] Rothfels, K, 2011-11-11 |
| modified | [InstanceEdit:8948629] Rothfels, Karen, 2016-11-14 |
| text | ADRBK1 (also known as GRK2) is phosphorylated at serine 29 in vitro and in vivo by the alpha, gamma and delta isoforms of PKC. PKC-mediated phosphorylation at Ser29 increases ADRBK1 kinase activity towards GPCR substrates, contributing to GPCR desensitization. Phosphorylation at Ser29, which falls within the calmodulin-binding region of ADRBK1, abolishes the inhibitory effect of calmodulin on ADRBK1 kinase activity. |
| (summation) | [Reaction:111970] PKC phosphorylates GRK2 [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by ADRBK1 (also known as GRK2) is phosphorylated at serine 29 i... (1986604)
