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Details on Person protein serine/threonine kinase activity of mTORC2:PIP3 [plasma membrane]

Class:Id	CatalystActivity:198624
_displayName	protein serine/threonine kinase activity of mTORC2:PIP3 [plasma membrane]
_timestamp	2026-01-26 20:58:35
activeUnit	[EntityWithAccessionedSequence:165662] MTOR [cytosol] [Homo sapiens]
activity	[GO_MolecularFunction:4028] protein serine/threonine kinase activity
created	[InstanceEdit:198616] Jassal, B, 2007-06-29 07:57:48
modified	[InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9658105] Weiser, JD, 2019-08-09 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9666277] Weiser, JD, 2019-11-04 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9676538] Cook, Justin, 2020-02-17 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9689079] Cook, Justin, 2020-05-15 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9757984] Weiser, JD, 2021-11-08 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9767390] Wright, Adam, 2022-02-25 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9773515] Weiser, Joel, 2022-05-04 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9909910] Weiser, Joel, 2024-05-14 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9917728] Weiser, Joel, 2024-08-09 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9926726] Weiser, Joel, 2024-11-03 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9939161] Weiser, Joel, 2025-02-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9948552] Weiser, Joel, 2025-05-21 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9963749] Weiser, Joel, 2025-08-15 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9970792] Weiser, Joel, 2025-10-31 [InstanceEdit:9980238] Orlic-Milacic, Marija, 2026-01-26 [InstanceEdit:9980269] Orlic-Milacic, Marija, 2026-01-26 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9983308] Weiser, Joel, 2026-02-22 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15 [InstanceEdit:9989150] Weiser, Joel, 2026-05-15
physicalEntity	[Complex:9980228] mTORC2:PIP3 [plasma membrane] [Homo sapiens]
(catalystActivity)	[Reaction:198640] mTORC2 phosphorylates AKT at S473 [Homo sapiens] [Reaction:2243938] AKT1 E17K mutant is phosphorylated by TORC2 complex [Homo sapiens] [Reaction:6795290] mTORC2 phosphorylates SGK1 [Homo sapiens] [Reaction:9860800] mTORC2 phosphorylates AKT1 on serine-473 [Homo sapiens] [Reaction:9980243] NICD1 positively regulates mTORC2-mediated phosphorylation of AKT at S473 [Homo sapiens]
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No pathways have been reviewed or authored by protein serine/threonine kinase activity of mTORC2:PIP3 [plasma membrane] (198624)