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Details on Person AKT phosphorylates IKKalpha

Class:IdReaction:198611
_displayNameAKT phosphorylates IKKalpha
_doReleaseTRUE
_timestamp2017-10-06 16:31:19
authored[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
catalystActivity[CatalystActivity:198368] protein serine/threonine kinase activity of p-T,p-S-AKT [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:198616] Jassal, B, 2007-06-29 07:57:48
goBiologicalProcess[GO_BiologicalProcess:172430] phosphatidylinositol 3-kinase/protein kinase B signal transduction
input[SimpleEntity:113592] ATP [cytosol]
[EntityWithAccessionedSequence:168104] CHUK [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:199398] NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
modified[InstanceEdit:199242] Jassal, B, 2007-07-10 07:58:07
[InstanceEdit:199370] Jassal, B, 2007-07-10 08:08:36
[InstanceEdit:201539] Jassal, B, 2007-08-21 12:50:53
[InstanceEdit:202667] Jassal, B, 2007-11-08 15:44:30
[InstanceEdit:211298] Jassal, B, 2008-01-30 10:40:56
[InstanceEdit:215417] Jassal, B, 2008-02-28 15:14:23
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:1262966] Jassal, B, 2011-05-06
[InstanceEdit:1273428] Jassal, B, 2011-05-11
[InstanceEdit:1667628] Orlic-Milacic, Marija, 2011-10-14
[InstanceEdit:6797594] Orlic-Milacic, Marija, 2015-09-14
[InstanceEdit:9014477] Orlic-Milacic, Marija, 2017-07-28
[InstanceEdit:9024715] Orlic-Milacic, Marija, 2017-10-06
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameAKT phosphorylates IKKalpha
output[SimpleEntity:29370] ADP [cytosol]
[EntityWithAccessionedSequence:198615] p-T23-CHUK [cytosol] [Homo sapiens]
precedingEvent
releaseDate2008-03-12
reviewed[InstanceEdit:202668] Greene, LA, 2007-11-08 15:39:37
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359521] R-HSA-198611.5
summation[Summation:198643] AKT mediates IKKalpha (Inhibitor of nuclear factor kappa B k...
(hasEvent)[Pathway:198323] AKT phosphorylates targets in the cytosol [Homo sapiens]
(normalReaction)[Reaction:2400001] AKT1 E17K mutant phosphorylates CHUK (IKKalpha) [Homo sapiens]
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No pathways have been reviewed or authored by AKT phosphorylates IKKalpha (198611)