Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person PI3K/AKT signalling is a major regulator of neuron survival...
| Class:Id | Summation:198205 |
|---|---|
| _displayName | PI3K/AKT signalling is a major regulator of neuron survival... |
| _timestamp | 2011-07-21 13:18:42 |
| created | [InstanceEdit:198207] Jassal, Bijay, 2007-05-21 |
| modified | [InstanceEdit:198702] 2007-07-10 08:01:56 [InstanceEdit:202099] Jassal, B, 2007-10-18 12:39:52 [InstanceEdit:202683] Jassal, Bijay, 2007-11-08 [InstanceEdit:1458444] D'Eustachio, P, 2011-07-21 |
| text | PI3K/AKT signalling is a major regulator of neuron survival. It blocks cell death by both impinging on the cytoplasmic cell death machinery and by regulating the expression of genes involved in cell death and survival. In addition, it may also use metabolic pathways to regulate cell survival.The PI3K/AKT pathway also affects axon diameter and branching (Marcus et al, 2002) and regulates small G proteins like RhoA (Vanhaesebroeck, B and Waterman, MD, 1999), which control the behaviour of the F-actin cytoskeleton. Moreover, through its connection with the TOR pathway, it promotes translation of a subset of mRNAs. |
| (summation) | [Pathway:198203] PI3K/AKT activation [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by PI3K/AKT signalling is a major regulator of neuron survival... (198205)
