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Details on Person Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2

Class:Id	Reaction:1981120
_displayName	Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2
_doRelease	TRUE
_timestamp	2024-07-16 19:49:29
authored	[InstanceEdit:913966] Jupe, S, 2010-07-20
catalystActivity	[CatalystActivity:1981159] procollagen galactosyltransferase activity of COLGALT1,COLGALT2:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen]
compartment	[Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:1981143] Jupe, S, 2011-11-09
edited	[InstanceEdit:2247551] Jupe, S, 2012-05-14
input	[Complex:8948218] COLGALT1,COLGALT2:Lysyl hydroxylated collagen propeptides [endoplasmic reticulum lumen] [Homo sapiens] [SimpleEntity:1981137] UDP-Gal [endoplasmic reticulum lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:1981180] Core glycosylation of collagen is initiated by two beta(1-O)galactosyltransferases [LiteratureReference:1981171] The human collagen beta(1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum localized protein
modified	[InstanceEdit:1981173] Jupe, S, 2011-11-09 [InstanceEdit:2022095] Jupe, S, 2011-11-25 [InstanceEdit:2023006] Jupe, S, 2011-12-01 [InstanceEdit:2023592] Jupe, S, 2011-12-09 [InstanceEdit:2025679] Jupe, S, 2011-12-14 [InstanceEdit:2193145] Jupe, S, 2012-04-12 [InstanceEdit:2247895] Jupe, S, 2012-05-14 [InstanceEdit:2267313] Jupe, S, 2012-05-24 [InstanceEdit:2268948] Jupe, S, 2012-05-25 [InstanceEdit:8948235] Jupe, Steve, 2016-11-11 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9915824] D'Eustachio, Peter, 2024-07-16
name	Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2
output	[Complex:2023003] COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides [endoplasmic reticulum lumen] [Homo sapiens] [SimpleEntity:158602] UDP [endoplasmic reticulum lumen]
precedingEvent	[Reaction:8948228] COLGALT1,COLGALT2 bind Lysyl hydroxylated collagen propeptides [Homo sapiens] [BlackBoxEvent:8948232] Lysyl hydroxylated collagen propeptides dissociate from Lysyl hydroxylases [Homo sapiens]
releaseDate	2012-06-12
reviewed	[InstanceEdit:2267224] Canty-Laird, EG, 2012-05-24
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294977] R-HSA-1981120.4
summation	[Summation:1981178] Hydroxylysine glycosides are specific to collagen. Collagen ...
(hasEvent)	[Pathway:1650814] Collagen biosynthesis and modifying enzymes [Homo sapiens]
(precedingEvent)	[BlackBoxEvent:8948231] COLGALT1,COLGALT2:Galactosyl-hydroxylysyl collagen propeptides dissociates [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9782445] Update Tracker - [Reaction:1981120] Galactosylation of collagen propeptide hydroxylysines by procollagen galactosyltransferases 1, 2. - v59:[add_removeInput]
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