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Details on Person NOTCH1 binds DLL/JAG ligand in cis

Class:Id	Reaction:1980138
_displayName	NOTCH1 binds DLL/JAG ligand in cis
_doRelease	TRUE
_timestamp	2024-06-03 14:18:49
authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1980137] Orlic-Milacic, M, 2011-11-08
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06
inferredFrom	[Reaction:2076711] rDll1 binds NOTCH1 in cis [Homo sapiens] [Reaction:2076706] Serrate binds Notch in cis [Drosophila melanogaster]
input	[Complex:157027] NOTCH1 [plasma membrane] [Homo sapiens] [DefinedSet:157643] DLL/JAG [plasma membrane] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:2076202] Orlic-Milacic, M, 2012-01-26 [InstanceEdit:2076712] Orlic-Milacic, M, 2012-01-27 [InstanceEdit:2077246] Orlic-Milacic, M, 2012-01-27 [InstanceEdit:2122946] Orlic-Milacic, M, 2012-02-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9911644] Orlic-Milacic, Marija, 2024-06-03
name	NOTCH1 binds DLL/JAG ligand in cis
output	[Complex:1980055] NOTCH1:DLL/JAG [plasma membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:1912382] Mature NOTCH heterodimer traffics to the plasma membrane [Homo sapiens] [Reaction:1912369] NOTCH precursor cleaved to form mature NOTCH [Homo sapiens]
releaseDate	2012-03-13
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2158234] R-HSA-1980138.3
summation	[Summation:2077244] Binding of NOTCH1 to DLL/JAG ligands expressed in the same c...
(hasEvent)	[Pathway:2122948] Activated NOTCH1 Transmits Signal to the Nucleus [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9919370] Update Tracker - [Reaction:1980138] NOTCH1 binds DLL/JAG ligand in cis - v90:[addLiteratureReference, modifyText]
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